ID A0A093G2R6_DRYPU Unreviewed; 377 AA.
AC A0A093G2R6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Hydroxylysine kinase {ECO:0000256|ARBA:ARBA00040505};
DE EC=2.7.1.81 {ECO:0000256|ARBA:ARBA00038873};
DE Flags: Fragment;
GN ORFNames=N307_11153 {ECO:0000313|EMBL:KFV61079.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV61079.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV61079.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV61079.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-
CC lysine. {ECO:0000256|ARBA:ARBA00037368}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine +
CC GDP + H(+); Xref=Rhea:RHEA:19049, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:37565, ChEBI:CHEBI:57882, ChEBI:CHEBI:58189,
CC ChEBI:CHEBI:58357; EC=2.7.1.81;
CC Evidence={ECO:0000256|ARBA:ARBA00036820};
CC -!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase family.
CC {ECO:0000256|ARBA:ARBA00006219}.
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DR EMBL; KL214718; KFV61079.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093G2R6; -.
DR STRING; 118200.A0A093G2R6; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR21064:SF1; HYDROXYLYSINE KINASE; 1.
DR PANTHER; PTHR21064; UNCHARACTERIZED; 1.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KFV61079.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Transferase {ECO:0000313|EMBL:KFV61079.1}.
FT DOMAIN 37..284
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
FT NON_TER 377
FT /evidence="ECO:0000313|EMBL:KFV61079.1"
SQ SEQUENCE 377 AA; 41974 MW; C780934072D3B722 CRC64;
MSSGNDCQSP ALTKPALGEK EVTELIDRVF GLKVSWIRPL PSYDDQNFHV GVLGNQGVSE
SADEYVLKIT NSEDSQEPDL IEVQTQAMMF LSNEGFPSAT PYLTKDGNIM SLESGGTGPG
NKKYMVRLLT YLPGIPVAKI ATNAQIFYEI GQLAARLDKT LSEKFYHPSV KSLHRGQFIW
NLANVPLLDQ YIYALGQNKY REVVEQVIEQ FKGTVIPKLS SFRPCINHGD LNDHNILVDS
SSASLENLQY NVSGILDFSD MSYGYYVFEV AIAIMYMMIE SPDPLGVGGH VLAGFESILP
LTEEERGALF LLVCGRFSQS LVIAAHTALL YPENKEYLTI TARTGWKHLM RMFEVGQEVV
EQTWFETARA YANHASA
//
