ID A0A093G3U8_DRYPU Unreviewed; 501 AA.
AC A0A093G3U8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059};
DE EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};
DE Flags: Fragment;
GN ORFNames=N307_03759 {ECO:0000313|EMBL:KFV61469.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV61469.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV61469.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV61469.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC Evidence={ECO:0000256|RuleBase:RU362059};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362059}; Single-
CC pass membrane protein {ECO:0000256|RuleBase:RU362059}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|RuleBase:RU003718}.
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DR EMBL; KL214744; KFV61469.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093G3U8; -.
DR STRING; 118200.A0A093G3U8; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF140; UDP-GLUCURONOSYLTRANSFERASE 2A1; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU003718}; Membrane {ECO:0000256|RuleBase:RU362059};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003718};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362059};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362059}.
FT TRANSMEM 475..498
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362059"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV61469.1"
FT NON_TER 501
FT /evidence="ECO:0000313|EMBL:KFV61469.1"
SQ SEQUENCE 501 AA; 57235 MW; D0A93C6800206EE6 CRC64;
AFCGKVVVWP TDGSHWINIK VLLEELVLRG HEVTVLVPSS NLLIDYQDTS SPFTFEVLQV
PFTQKNLDDA MDNFLNLWLN EASNLSTWEI MWKMKEELEV FTNMSKQTFD TLMTNSQLVA
RLQQARFDVL IADPLVVGGE LVAELLAIPF VYSFRFSDAN VVERLCGGLP APPSYVPAST
KGLTDRMSFV ERLQNFLFYF YMDFFFLTFW RDEWDGYYSN VLGRPTTLCE TMGKAEIWLI
RTYWDFEFPR PFLPNFEFVG GLHCQPAKPL PKEMEAFVQS SGEHGIIVFS LGSMVYNLTD
EKSNMIARAL SQLPQKVLWR YKGKKPEALG SNTRIYDWIP QNDLLGHPLT KAFITHGGTN
GIYEAIYHGV PMVGIPMFAD QHDNIAHMKA KGAAAALDFS TMTTQDLVDA LNTVITNSTY
KENALRLSKI HHDQPLKPLD RAVFWIEFVM RHKGAKHLRP AAHDLTWYQY HCLDVLAFLF
ACTATTVFLL TKCCLFCCRK C
//
