ID A0A093GDB1_DRYPU Unreviewed; 1298 AA.
AC A0A093GDB1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Pleckstrin homology domain-containing family H member 1 {ECO:0000313|EMBL:KFV64862.1};
DE Flags: Fragment;
GN ORFNames=N307_04140 {ECO:0000313|EMBL:KFV64862.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV64862.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV64862.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV64862.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL215503; KFV64862.1; -; Genomic_DNA.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13206; FERM_C-lobe_PLEKHH1_PLEKHH2; 1.
DR CDD; cd17178; FERM_F1_PLEKHH1; 1.
DR CDD; cd00821; PH; 1.
DR CDD; cd13282; PH1_PLEKHH1_PLEKHH2; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22903:SF4; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 1; 1.
DR PANTHER; PTHR22903; PLEKHH PROTEIN; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 508..602
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 617..725
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 761..915
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 926..1259
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 330..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 27..97
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 429..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV64862.1"
FT NON_TER 1298
FT /evidence="ECO:0000313|EMBL:KFV64862.1"
SQ SEQUENCE 1298 AA; 145924 MW; F56F23B61903E4A2 CRC64;
QVRVMEEKIK LTNVKTSEFD STLHRKYQEL MGIVQRKEDL INRLETQLAK QKQLRTEEAK
IVQEKAAKIK EWVTFKLREL ELENYHLKNC NQKLTEQIEA LRDTLQGKCV HVPLWPSNHY
RSANQHYWVA FLNLSEISTC DSEVSSRVAL FLRNCSAVST LQQAALDGTR FSDDLSARFH
SHWLDSSSSG KIMTMLEDHL QTAEPALAVS TPTVPARSLC PGRERGLGNS MTFPKIRTPN
TPRDSIQLAK RHYSQPQPGA NSFHCVMSLE ASTFQPITDS PVCHGQVKET DIDDDGVLEK
METEHGLLCE EAGTCEEINH LFAGQREAGS SETGILDPGG KPPTPPLHRL PSWESRIYAV
AKSGMRLSEV AVVNDTSNCL SNFSCSPSGP FSCLIYRNVT VPVYTTLKGK ATQISNVPFL
DESSGSDDDC GSHASFRTST AGSENRKASM PGSPRAVKRG VSMSSLSSES DYAIPPDAYS
LDGDYSEPEH KLQRTSSYST DGGICTEPME KSGYLLKMGS QVKMWKRRWF VLRNRQIMYY
KSPSDVIHKP QGQMELNSSC QIVRGEGSQT FQLVTEKRTY FLTADSPNIL EEWIHVLQSI
LRVQVTGPVG VPHSDAKPTV KGWLTKVKHG HSKLVWCALI GKTFYYYRNH EDKCPLGHLP
MRESKVEEVD RSCDSDEDYE ATGGGLLSSH CTLVIHPQDQ SPTYLLIRTK QEKNTWLYHL
TVAAGSSNAT VGTSYEQLIG KLLDAEGDPN SPLWKHPMLC YSKDGLHTSL TTLPSEALQT
EALKLFKSCQ LFINVPVEAS SIDYHVSLAQ TALQVCLTHT ELQNEVYCQL VKQTSCRQPQ
NHSVIQCWQL LALCAPLFLP QHHFLWYIKQ HFQRHADPRS EIGKYAIYCQ RSVDRTVQTG
EREAKPSRME IVSILLRNPY HHSLPFSIPV HFMNGTYQVV GFDGSSTVDE FIQRLNQETG
MRKPSHTGFS LFTDDPSGKN LEHCLQGNMK ICDVISKWEQ ALKELHPGKY EGGTRIVKLT
YKNRLYFRSQ AKGETDRERL LLAFQVSNEI ANGRFPVNKE LALEMVALMA QVEYGDLDRP
GSSNPGGTSP SKMQHLLHQV LDKFYPKCYK QNITPEQLRQ LADRLATKWI VLQGCSPPEC
IRIYLTVARK WPLFGTKIFA AKPVLPSLLE DYPVWIAVNE DGISILDYNT MHLKVSYSYS
SVLTFGGCRE DFMIVVSQTK ERSSGKNSTE KLLFTMAIPK IVEATLLIAS YINFRSTPSL
LSSTQPCQSK APANKLWETE SRCSFPSVPR STKGPTLL
//
