ID A0A093GDB7_DRYPU Unreviewed; 679 AA.
AC A0A093GDB7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Fibulin-1 {ECO:0000256|ARBA:ARBA00021554};
DE Flags: Fragment;
GN ORFNames=N307_13412 {ECO:0000313|EMBL:KFV64872.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV64872.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV64872.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV64872.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- SIMILARITY: Belongs to the fibulin family.
CC {ECO:0000256|ARBA:ARBA00006127}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL215504; KFV64872.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093GDB7; -.
DR STRING; 118200.A0A093GDB7; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016504; F:peptidase activator activity; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR CDD; cd00017; ANATO; 1.
DR CDD; cd00054; EGF_CA; 4.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR InterPro; IPR000020; Anaphylatoxin/fibulin.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR017048; Fibulin-1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24034; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24034:SF198; RE68558P; 1.
DR Pfam; PF01821; ANATO; 1.
DR Pfam; PF12662; cEGF; 2.
DR Pfam; PF07645; EGF_CA; 5.
DR PIRSF; PIRSF036313; Fibulin-1; 1.
DR SMART; SM00104; ANATO; 3.
DR SMART; SM00181; EGF; 9.
DR SMART; SM00179; EGF_CA; 9.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS01177; ANAPHYLATOXIN_1; 1.
DR PROSITE; PS01178; ANAPHYLATOXIN_2; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 3.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 8..42
FT /note="Anaphylatoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS01178"
FT DOMAIN 50..83
FT /note="Anaphylatoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS01178"
FT DOMAIN 85..117
FT /note="Anaphylatoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS01178"
FT DOMAIN 332..374
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 375..416
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 417..456
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV64872.1"
FT NON_TER 679
FT /evidence="ECO:0000313|EMBL:KFV64872.1"
SQ SEQUENCE 679 AA; 75526 MW; 3EFD83EF040C8A26 CRC64;
ADLTMEECCE KGIEWANKNR ICTSLPFISE SRECSMTQFQ CCRSQLEKQY CSDGIEYANV
REECDSNTGE NSTCEAQYFK TCCYCCLLGK VAEIQGQGCE PNPKIGYQCG IVFRACCVKS
QEGIDVSISD DVPEKEQVEI SKEELDQEDP YLHDGCRGGG PCSQQCRDTG SSYVCSCFVG
YQLQPDGVNC EDINECITGT HSCGIGQTCV NTLGSFRCQR DTSCGTGYEL TDDSRCKDID
ECETGTHNCP PDFICQNTPG SFRCRPKLQC MNGFIQDALG NCIDINECLS TNMPCPAGQI
CINTDGSYMC QRISPNCGRG YHLNEDGTRC VDVDECSSSN QPCGEGHVCI NAPGSYRCEC
KSGYSFDVIS RTCIDINECR RYPGRLCAHK CENTPGSYYC TCTMGFKLSA DGRSCEDLNE
CESSPCSQEC ANVYGSYQCY CRRGFQLSDI DGISCEDIDE CALPTGGHIC SFRCINVPGS
FQCTCPSTGY RLAPNARNCQ DIDECVAESH NCSFNETCFN IQGGFRCLSL ECPENYRKSG
DTIRLEKTDT IRCIKSCRPN DVICMLDPVH TISHTVISLP TFREFTRPEE IIFLRAITPT
YPANQADIIF DITEGNLRDS FDIIKRYMDS MTVGVVRQVR PIVGPFHAIL KLEMNYVMGG
VVSHRNIVNV HIFVSEYWF
//
