ID A0A093GHK2_DRYPU Unreviewed; 556 AA.
AC A0A093GHK2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 22.
DE SubName: Full=NADPH-dependent diflavin oxidoreductase 1 {ECO:0000313|EMBL:KFV68708.1};
GN ORFNames=N307_07535 {ECO:0000313|EMBL:KFV68708.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV68708.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV68708.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV68708.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL216277; KFV68708.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093GHK2; -.
DR STRING; 118200.A0A093GHK2; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.360; -; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR003097; CysJ-like_FAD-binding.
DR InterPro; IPR001094; Flavdoxin-like.
DR InterPro; IPR008254; Flavodoxin/NO_synth.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR19384:SF10; NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1; 1.
DR PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00667; FAD_binding_1; 1.
DR Pfam; PF00258; Flavodoxin_1; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR PRINTS; PR00369; FLAVODOXIN.
DR PRINTS; PR00371; FPNCR.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875}.
FT DOMAIN 6..150
FT /note="Flavodoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS50902"
SQ SEQUENCE 556 AA; 61846 MW; 1FA99127A888308E CRC64;
MAERKVLVLF GSQTGTAEDA AERIGREAKR RHFQCRVEAL DSYDVANLIN EPLVVFVCAT
TGQGDPPDNM KTFWRFLFRK SLSPSSLCQL DYAVLGLGDS SYPKFNFIAK KLHKRLLQLG
GNPLLPVALG DDQHDLGPDA VIDPWLLALW DKVLALYPLP PGLEIISPDV CAETSPCVWS
CWAVLSMAKP GACGSVSPAH GPALALLRSQ LEHCVQFWAP PVQEGQGCAG ECPREAVRVL
ESLEPVWFSA GDVVMIQPQN SPEDVQQFCQ LLCLQPDRLF VLKPTEPGTA LPALLPQPCS
IRQLLTHHLD LACVPRRSFF QLLSCLSTHP LEREKLQELS SAQGQEELYS YCNRPRRTTL
EVLWDFPHTS CAIPPDYLLD LIPRISSPSL LLPSSSEHRV PLQLALSCCF SPSSLSLPIP
VPLCPTAGCF WCPAAGDVWV PLWVKKGGLK FPADPDTPVV MIGPGTGVAP FRAAIQERVA
QGRRGNFLFF GCRQRSKDFY CREDWEELVA KGFLTLFTAF SRDQEEKVYV QHRIREQRRL
VWELLNCRGA HLYLAG
//
