ID A0A093GKJ2_DRYPU Unreviewed; 880 AA.
AC A0A093GKJ2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Laminin subunit alpha-2 {ECO:0000313|EMBL:KFV70785.1};
DE Flags: Fragment;
GN ORFNames=N307_06213 {ECO:0000313|EMBL:KFV70785.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV70785.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV70785.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV70785.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; KL216661; KFV70785.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093GKJ2; -.
DR STRING; 118200.A0A093GKJ2; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00055; EGF_Lam; 6.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF291; LAMININ SUBUNIT ALPHA-2; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00053; Laminin_EGF; 7.
DR Pfam; PF00055; Laminin_N; 1.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00180; EGF_Lam; 7.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01248; EGF_LAM_1; 3.
DR PROSITE; PS50027; EGF_LAM_2; 4.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022869};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Secreted {ECO:0000256|ARBA:ARBA00022869}.
FT DOMAIN 1..249
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 433..481
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 502..687
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DOMAIN 721..770
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 771..828
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 829..880
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DISULFID 452..461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 740..749
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 799..808
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 853..862
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 865..879
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV70785.1"
FT NON_TER 880
FT /evidence="ECO:0000313|EMBL:KFV70785.1"
SQ SEQUENCE 880 AA; 96325 MW; 7877A58D834D9536 CRC64;
GLFPAVLNLA TNALITTNAT CGEKGREMYC KLVEHVPGQP ARHPQCRICD QRSRVPHQRH
PITNAIDGKN TWWQSPSIQN GIEYHYVTIT LDLQQVFQIA YVIVKAANSP RPGNWILERS
LDGEDYQPWQ YYAITDSECL TRYNVPPRPG TPSYLKDDEV ICTSYYSKIH PLENGEIHTS
LINGRPSADD PSQVLLEFTS ARFIRLRFQR IRTLNADLMM FAHKDPKEID PIVTRRYYYS
IKDISVGGMC ICSGHAKACP LDPATNKSVC QCEHNTCGET CDRCCPGFHQ RPWQAGTFLE
KHECEPCNCH GKTEECYYDQ GVAERRQSLN VQGEYVGGGV CVNCTNHTGC QPCLDGYFRP
QGVSAPALAS PCAGCSSHRC SASRETENGD EEEILDTEGD MLPGFCHCKT GYAGESCNRC
ALGYTGYPEC LPCNCSVQGS MNADPCIGPC VCKEHTEGEN CDRCKPGFFN LQQSNPKGCE
ECFCSGKTDV CTPSHLTYRR IEDMSGWYLT DLPGLTRVSP KQQRVDGHQQ LSISNVAASQ
VLPQAYYWSA PSSYLGNKVA AAGGHLKFTV SYDFTEEEET VQVMVQSDVI IEGGGLRIST
PEEGIHLQPS EEHTAEIVLE PGSFSVHGTD APVSRRDFMT ILANVKRILL RATYTYGMNA
IYRLRSVSME AADHSSAGRK VASAVELCDC PPGYDGTSCE SCWPGHRRVN GTVFGGLCAP
CTCFGHAAAC DDLTGECLDC QHNTGGPYCD RCLPGFYGDP TKGTAEDCQL CACPLNIPSN
NFSPTCHFDR SRGLLCDECP AGYVGARCER CAEGYFGQPL IPGGSCQPCP CNDNLDFSIP
GSCDSLSGAC LRCKAGTAGQ YCERCADGFF GDALDARGCQ
//
