ID A0A093GLW3_DRYPU Unreviewed; 730 AA.
AC A0A093GLW3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Leucine-rich repeat-containing G-protein coupled receptor 4 {ECO:0000313|EMBL:KFV68002.1};
DE Flags: Fragment;
GN ORFNames=N307_11882 {ECO:0000313|EMBL:KFV68002.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV68002.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV68002.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV68002.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL216075; KFV68002.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093GLW3; -.
DR STRING; 118200.A0A093GLW3; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
DR CDD; cd15361; 7tmA_LGR4; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR002131; Gphrmn_rcpt_fam.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24372; GLYCOPROTEIN HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24372:SF67; LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 4.
DR PRINTS; PR00373; GLYCHORMONER.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 13.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS51450; LRR; 5.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFV68002.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 452..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 616..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 697..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 468..714
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV68002.1"
FT NON_TER 730
FT /evidence="ECO:0000313|EMBL:KFV68002.1"
SQ SEQUENCE 730 AA; 81263 MW; 586B558EFB483DB8 CRC64;
RLAGNDLSFI HPKALSGLKE LKVLTLQNNQ LKTVPNEAIR GLSGLQSLRL DANHITAIPE
DSFEGLVQLR HLWLDDNSLT EVPIYPLSNL PSLQALTLAL NKITHIPDYA FTNLSSLVVL
HLHNNKIKTI GKHCFDGLDN LETLDLNYNN MVEFPEAIKA LPNLKELGFH SNYISIIPDG
AFAGNPLLRT IHLYDNPLSF VGNSAFQNLS DLHSLVIRGA SMVQWFPNLT GTVNLESLTL
TGTKISSIPG NLCQEQKVLR TLDLSYNSIK ELPSFKGCHS LEEISLQHNQ IHEIKEDTFQ
GLSALRILDL SRNRIHQIHK EAFTTVGAIV NLDLSFNELT SVPTEGLSGL NQLKLAGNSE
LKEALAAKNF AKLRSLSVPY AYQCCAFWGC DSYLNSNAED SRHQDQGVLV DREKADTDAL
RNEENEELGQ TIIHCTPATG AFKPCEYLLG SWMIRLTVWF IFLVALFFNL LVMLTIFASC
APLPSSKLFI GLISVSNLFM GVYTGILTFL DAVSWGRFAE FGIWWETGSG CRVAGFLAVF
SSESAIFFLM LAAVERSFSA KEIIKKGKSN RHKQFQVAAV FAFLCAVVAG CLPLFYKAEY
SASPLCLPFP TGETPSLGFT VTLVLLNSLA FLLMVVIYTK LYCNLEKEDL SENSQSSMIK
HVAWLIFTNC IFFCPVAFFS FAPLITAISI SPEIMKSVTL IFFPLPACLN PVLYVFFNPK
FKEDWKLLRR
//
