ID A0A093GRP8_DRYPU Unreviewed; 2478 AA.
AC A0A093GRP8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Nuclear receptor corepressor 1 {ECO:0000256|ARBA:ARBA00044171};
GN ORFNames=N307_07335 {ECO:0000313|EMBL:KFV69469.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV69469.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV69469.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV69469.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N-CoR nuclear receptor corepressors family.
CC {ECO:0000256|ARBA:ARBA00010097}.
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DR EMBL; KL216427; KFV69469.1; -; Genomic_DNA.
DR STRING; 118200.A0A093GRP8; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR CDD; cd00167; SANT; 2.
DR Gene3D; 1.20.5.430; -; 1.
DR Gene3D; 1.20.58.1880; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR031557; N-CoR_GPS2_interact.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR PANTHER; PTHR13992; NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR; 1.
DR PANTHER; PTHR13992:SF5; NUCLEAR RECEPTOR COREPRESSOR 1; 1.
DR Pfam; PF15784; GPS2_interact; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
DR PROSITE; PS51293; SANT; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Receptor {ECO:0000313|EMBL:KFV69469.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 438..489
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 625..675
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 628..679
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 632..679
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1042..1067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1103..1139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1459..1558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1702..1762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1779..1798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1920..1960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1982..2005
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2027..2046
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2056..2079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2108..2194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2206..2226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2316..2455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..575
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..625
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..703
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..736
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..825
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..904
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1046..1060
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1103..1121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1465..1522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1532..1548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1730..1762
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1920..1940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1946..1960
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2108..2148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2163..2180
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2328..2376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2385..2399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2409..2455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2478 AA; 275384 MW; F059A57CFEB903F9 CRC64;
MSSSGYPPNQ GAFSTEQSRY PTHSVQYTFP STRHQQEFAV PDYRSSHLEV SQATQLLQQQ
QQQQQQLRRR PSLLSEFHPG SDRPQERRTG YEQQFHPGPS QTDHDSLESK RPRLEQVSDS
HFQRVSAATV LPLVHPLQEG LRSADIKKDP AFGGKHEGPS SPISGQPCGE DQNASPSKLS
KEELIQSMDR VDREIAKVEQ QILKLKKKQQ QLEEEAAKPP EPERPVSPPP VEQKHRSIVQ
IIYDENRKKA EEAHKIFEGL GPKVELPLYN QPSDTKVYHE NIKTNQVMRK KLILFFKRRN
HARKQREQKI CQRYDQLMEA WEKKVDRIEN NPRRKAKESK TREYYEKQFP EIRKQREQQE
RFQRVGQRGA GLSATIARSE HEISEIIDGL SEQENNEKQM RQLSVIPPMM FDAEQRRVKF
INMNGLMEDP MKVYKDRQFM NVWTDHEKEI FKEKFVQHPK NFGLIASYLE RKNVPDCVLY
YYLTKKNENY KALVRRNYGK RRGRNQQQIA RPSQEEKVEE KVEEEKAEKA EKKEEEKKDE
EEKDEKEESK ENTKEKDKTE VAPEETEERE QATPRGRKTA NSQGRRKGRI TRSMTNEAAQ
ANAAAAAATE EPPPPLPPPP EPSSAEPVET SRWTEEEMEV AKKGLVEHGR NWAAIAKMVG
TKSEAQCKNF YFNYKRRHNL DSLLQQHKQK SSRRPREERD VSQCESVAST VSAQEDEDIE
ASNEEENPED SEGAENSSDT ESAPSPTPAE PAKPAEETPP ETAAPKVTTE ATAEQESTVK
PAPSTPPSTA QSVSTAESQA PEPQVKEEIN NEAEEPMEVD SRSHPVEAKP VITLPVHTKV
EPVETEMRLP ENIQVKIESD AKEREMEKPK EKSEPEEMDY SLSQQVNTAR QESHSDNDSS
ATCSADEEVD GEPDRQGIFS RESKPSLLNP PGSILVSSTI KQGQMDLQQL HHRAAVIPPM
VSCSPCTVPV GTPVSGYALY QRHIKAMHES ALLEEQRQRQ EQLDMEYRSA VSPCGTSKSP
SVEWEVLQPA PHQVITNIPE GVRLPTTRPT RPPPPLIPSS KTSVPSEKPS FIMGGSISQG
TPGTYLTSHS QASYTQETAK PSVGSISLGL PRQQESAKSA SLPYIKQEEF SPRSQNSQPE
GLLVRAQHES VVRGTATIQE GSITRGTPTS KVSVETIPSL RGSITQGTPA LSQSGIAADA
LLKGTITRLA TEDSSPEKCR EEASAKGHVI YEGKSGHILS YDAIKNVREG TRSPRTAHEI
SLKRSYDTME GNIKQGMSMR ESPVSAPLEG LICRALPRGS PHAELKERTV LSGSIMQGTP
RATAESFEEG LKYPKQIKRE SPPIRTFEGA ITKGKPYDGV TTIKEMGRSI HEIPRQDLLS
QESRKTPEMV QTSRPIIEGS ISQGTPIKYE SNSGQSAIKH NVKSLITGPS KLPRGMPQLE
MVPENVKVVE RGKYEDVKTG DAVRSRHTSV VSSGPSVLRS TLHETPKSQL SPGIYDDTNA
RRTPVNYQSP MSRSSPMMNR VSEAGISSGK PANHERKNTL TPTQRESVPA KSPVPGVDPV
VTHSPFDPHH RGATPEVYRS HLPPHLDPAM PFHRALDPAA AAYLFQRQLS PTPGYPSQYQ
LYAMENTRQT ILNDYITSQQ MQVNLRPDVT RGLSPREQTL ALPYAGARGI IDLNNMAPTI
LVPHPGGTST PPMERITYIP GTQLTFPPRP YNPASLSPGH PTHLAASAAA NAERERERER
EKERERERER ERERERERER ERERIASVPV LTTHCTVRCT EQPGRPGSHG YVRSPSPSVR
SQENILQQRP SIFQGTNGTS VITPLDPAAQ LRIMYLTPGA PSITQGLPAS RYNTAADALA
ALVDAAASAP QMEVAKAKEN KHEGTRIEEN MGRRSAVVTE QQQMEQKTLE VEKRPVQCPY
TSANFSGGKS QGQSSTVVYS EAGKEKGPPP KSRYEEELRT RGKTTITAAN FIDVIITRQI
ASDKDARDRG SQSSDSSSSL SSHRYEAPGD AIEVISPANS PVPAQEKLQP YQQETPKASQ
AENDPNRQYE GTIHRYRTPQ EPPSPQQPPP PSSQAEGMAH VPRTHRLITL ADHICQIITQ
DFARNQAATQ ASLQPPTTTF QNSTPAPTPV STRAKTSNRY SPEAQSPSVH HQRPGARVSP
ENLSDKSRGR PGKSPERSHV SSEPYEPISP PQVPVLHEKQ ENVILLSQRT EPTEQRTDSR
SPGSISYLPS FFTKLENTSP MVKSKKQEIF RKLNSSGGGD SDMATAQPGT EIFNLPAVTT
SGAVSSRGHS FADPASNLGL EDIIRKALMG NFDDKSEEHG VVMPQSIAVA PGSSSAAVSA
SNEPRREEAN PSPNSGGGVS KQKLIGKSNS RKSKSPIPGQ GYLGTERPSS VSSVHSEGDY
HRQTPVWAWE DRPSSTGSTQ FPYNPLTMRM LSSTPPTSIA CAPPSMSQAT THQQNRIWER
EPAPLLSAQY ETLSDSDD
//
