ID A0A093GTU5_DRYPU Unreviewed; 1064 AA.
AC A0A093GTU5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative E3 ubiquitin-protein ligase HERC4 {ECO:0000313|EMBL:KFV72791.1};
GN ORFNames=N307_11468 {ECO:0000313|EMBL:KFV72791.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV72791.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV72791.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV72791.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL217011; KFV72791.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093GTU5; -.
DR STRING; 118200.A0A093GTU5; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR PANTHER; PTHR45622:SF58; HECT AND RLD DOMAIN CONTAINING E3 UBIQUITIN LIGASE 4, ISOFORM C; 1.
DR PANTHER; PTHR45622; UBIQUITIN-PROTEIN LIGASE E3A-RELATED; 1.
DR Pfam; PF00632; HECT; 1.
DR Pfam; PF00415; RCC1; 7.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS50237; HECT; 1.
DR PROSITE; PS00626; RCC1_2; 3.
DR PROSITE; PS50012; RCC1_3; 7.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT REPEAT 1..52
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 53..102
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 103..155
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 156..208
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 209..260
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 261..312
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 314..380
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 737..1064
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT ACT_SITE 1032
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 1064 AA; 119681 MW; 8E9B7168F0F55150 CRC64;
MLCWGNASFG QLGLGGIDEE IVLEPRRSDF FLNKRIRDVG CGLRHTVFVL DDGTVYTCGC
NDLGQLGHEK ARKRPEHVGA LDAQNIVAVS CGEAHTLALN DKGQVYAWGL ATDGQLGLPG
TEECIRVPRN IKSLSEIQIV QVACGYYHSL ALSKGSEVFS WGQNKYGQLG LGYEYKKQNS
PHMIKSLLGI PFAQIAAGGA HSFVLTLSGA IFGWGRNKFG QLGLNDDNDR YVPTLLKSLR
SQKVVHICCG EDHTAALTKE GGVFTFGAGG YGQLGHNSTS HEINPRKVFE LMGSVVTQIT
CGRQHTTAFV PSSGRIYSFG LGGNGQLGTG TTSNRKSPFT VKGNWLPYST QCPKTTDSEE
FYCVKRIFSG GDQSFAHYFY PQNMVLPDDF RYPDFLKQIW TVNEMFIQRL LSFPSGRLPV
EIANEIDGTF SSAGCLNGSF LALSNDDHYK TSTRFSGVDM NAARLLFHKL IQPDHTHIAQ
QVAASLEKNL IPKLTSSLPD VEALRLYLTL PECPLMSDPN NFTTLAIPFG TAILNLEKAP
LKVLENWWSV LEPPLFLKIV ELYKDVVVHL LKLCKIGVPA SERRILTNFL QTAFRVLEIL
HRVCICRLGQ VIQYDRFYIH EIQDLIDIRN DYVNWVQQQM FGMDVNHGLT EVRLVAIRFL
VQNTDGCYCL TRVLGYLLTQ NPLWLCFFLQ MAVDQAHRQN LSSLFLPVFE SVNPCLILMV
RRDNIVGDAV EVLRKTKNVD YKKPLKVIFV GEEAVDAGGV RKEFFLLIMR ELLDPKYGMF
RCYEESRLIW FSDKTFEDSD LFHLIGVVCG LAIYNFTIVD LPFPLALYKK LLNKKPSLDD
LKELMPDVGR GMQQLLDYPE DDIEEAFCLN FTITVENFGT TEIKELVPNG ADIPVAKQNR
QDFVDAYVDY IFNRSVASLF SAFHAGFHKV CGGKVLQLFQ PSELQAMVIG NTNYDWKELE
KSTEYKGEYW ADHPTIKIFW EVFHELSLEK KKQFLLFLTG SDRIPILGMK CVKLVIQPTG
GGEGYLPVAH TCFNLLDLPK YTDKETLKSK LIQAIDHYEG FSLV
//
