ID A0A093H1T2_STRCA Unreviewed; 696 AA.
AC A0A093H1T2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE SubName: Full=Protein-glutamine gamma-glutamyltransferase 6 {ECO:0000313|EMBL:KFV73047.1};
DE Flags: Fragment;
GN ORFNames=N308_08690 {ECO:0000313|EMBL:KFV73047.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV73047.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV73047.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV73047.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|PIRSR:PIRSR000459-2};
CC Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR000459-2};
CC -!- SIMILARITY: Belongs to the transglutaminase superfamily.
CC Transglutaminase family. {ECO:0000256|ARBA:ARBA00005968}.
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DR EMBL; KL205696; KFV73047.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093H1T2; -.
DR STRING; 441894.ENSSCUP00000004379; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR InterPro; IPR023608; Transglutaminase_animal.
DR InterPro; IPR013808; Transglutaminase_AS.
DR InterPro; IPR008958; Transglutaminase_C.
DR InterPro; IPR036238; Transglutaminase_C_sf.
DR InterPro; IPR001102; Transglutaminase_N.
DR PANTHER; PTHR11590; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR PANTHER; PTHR11590:SF50; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 6; 1.
DR Pfam; PF00927; Transglut_C; 2.
DR Pfam; PF01841; Transglut_core; 1.
DR Pfam; PF00868; Transglut_N; 1.
DR PIRSF; PIRSF000459; TGM_EBP42; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49309; Transglutaminase, two C-terminal domains; 2.
DR PROSITE; PS00547; TRANSGLUTAMINASES; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|PIRSR:PIRSR000459-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR000459-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Transferase {ECO:0000313|EMBL:KFV73047.1}.
FT DOMAIN 266..358
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT ACT_SITE 274
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 332
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 355
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT BINDING 395
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 397
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 444
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 449
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV73047.1"
FT NON_TER 696
FT /evidence="ECO:0000313|EMBL:KFV73047.1"
SQ SEQUENCE 696 AA; 78607 MW; AF4D96C601442528 CRC64;
FIDLTPTHIS WQPSVNAGAH HTDRYVNTEL TVRRGQAFAI TLYFNRPQQT GESLAFVTEI
GPSPSESHHT KAVFNLSEVG ASGWSAVQGP SESGYTNFTI TSPANAVIGR YNLILQVTSG
NKIFSRFLGQ FVMLFNPWCP GDDVYMANEN ERQEYVLNEN GIIFVGNAKY IEARGWYYGQ
FQDPLLNICL TMLDLSLYYR QDPAIDVSRR GDPKYVGRVI SSMINGNDND NGVLLGKWQG
SFHSHENPSR WDGSVVILQK WRQDNYKPVQ YGQCWVFAGV MCTVLRCLGI PTRLISNFNS
AHDVDRNLSI DKYYDSSGKS LNIGKDSTWD YHVWNESWFI RRDLGTLYNG WQVLDATPQE
QSKGLFQCGP ASVIAIKEGD VDLDYDTLFV YTEVNADCNR WIVYNDGTKK RVYCDTEIIG
RFISTKAVGS NSRVDVTYNY KYPEGSSEER QVYKKAWAKI FGSNVTERHR ESPSERSSET
IRNPGISGKF KLAEPPVFGK DITLILILNN LSFDHKTVKV DISASTILYT RRAVAEILQA
TTSVDLGSKQ GKHIQLKIPY SYYGKYLTTD KRIQVTALCE VMHMHGVKLL VEKTIILEDT
NIIIKVPRRV VVNKAVTLEI SYANPLPEPV NSCVLLVTLM NQQVKIHLAG LAPRERSRIY
FEFTPRRTGP LQLQVDFSCD KFSHVKGFVT IAVAPA
//
