ID   A0A093HCY1_STRCA        Unreviewed;      1253 AA.
AC   A0A093HCY1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=TBC1 domain family member 1 {ECO:0000313|EMBL:KFV80458.1};
DE   Flags: Fragment;
GN   ORFNames=N308_07723 {ECO:0000313|EMBL:KFV80458.1};
OS   Struthio camelus australis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV80458.1, ECO:0000313|Proteomes:UP000053584};
RN   [1] {ECO:0000313|EMBL:KFV80458.1, ECO:0000313|Proteomes:UP000053584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV80458.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL206236; KFV80458.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093HCY1; -.
DR   STRING; 441894.ENSSCUP00000009170; -.
DR   Proteomes; UP000053584; Unassembled WGS sequence.
DR   CDD; cd00934; PTB; 1.
DR   CDD; cd01269; PTB_TBC1D1_like; 1.
DR   Gene3D; 1.10.10.2750; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR   Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR   InterPro; IPR021785; DUF3350.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR000195; Rab-GAP-TBC_dom.
DR   InterPro; IPR035969; Rab-GAP_TBC_sf.
DR   PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR   PANTHER; PTHR47219:SF18; TBC1 DOMAIN FAMILY MEMBER 1 ISOFORM X1; 1.
DR   Pfam; PF11830; DUF3350; 1.
DR   Pfam; PF00640; PID; 1.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00462; PTB; 2.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR   PROSITE; PS01179; PID; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053584}.
FT   DOMAIN          318..397
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          905..1099
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   REGION          483..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          538..676
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          736..761
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1184..1253
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        492..509
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        549..593
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        610..624
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        654..676
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        736..756
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1253
FT                   /evidence="ECO:0000313|EMBL:KFV80458.1"
SQ   SEQUENCE   1253 AA;  142271 MW;  45ADA32FC4A2BB1F CRC64;
     MEPITFKVKK YQASSDLSAN FTLQLVGSLP VHSLTTMSML PWVVAEIRRL STESVKEEPS
     TSQIRLYVSP ASLRCEPDTG KNQQWDPLIC SSLFEYKPQH VHKLIHNSHD PSYFACLIKD
     GAANQQSVCY VFKADDQTKV PEIISSIRQA GKIARQEEFQ NNLSDVEDPF AKKFEVLFCG
     RVTVAHKNAP PALIDECIEK FNHASGTKKS DFNSLSQQHE TANNSGGFSF SDKFRSVFHP
     LVSEEEEKRP IRKSFSQPGL RSFAFKKDLQ DGGHRSNSFV RSFEEDAISL NLKSQLIYGH
     SVVQPTDIAE NRTMLFTIGQ SEVYLISPDT KKVAIEKSFK EISFCSQGIR HVDHFGFICR
     ESSENGGFHF VCYVFQCTDE ALVDEIMMTL KQAFTVAAVQ QTSKMQPQLC EGCPLQSLHK
     LCEKIEGLHP SKTKLELQKH LTTLSSQEQA SVFEEVKKLR PRNDQKENEL VISVLRNMYE
     EKQRDHVHTG EAKQTSQPPT ENAGNEGPSS TPRFRLDMLK NKAKRSLTES FENILSRGSK
     ARGPLDSSGS VDLESSTSST LSSTSKVSKA CQRLPTLPTE SSVKTSGSAG DLSSDRDSYP
     VEQAVKLPQQ SFRRRANTLS HLPMESQEPL EPVETSPPVP QRKLMRYHSV STETPHKRNS
     SGQLAPSPTL ARLNPSASSP NFFKYLRHNA SGEQSGHFTQ KSTSYRTALR KKLHSSSSVP
     NFLKFLAPVD ENNTSDFRST TSDYESKHSQ QAVGADSPVR TRRHSWRQQI FLRVATPQKA
     CDSPSRYDDY SELGELPPRS PLEPVCEDGP FGPVKEERKR TPLELRELWK KAIIQQILLL
     RMEKENQKLQ ASENNLQNRR LKLDYEEITP CLKDVTLIWE KMLSTPGRSK IKFDVEKIHS
     AAGQGVPRHH RGEIWKFLAE QYHLKHQFPS KQQPKDTPYK ELLKQLTSQQ HAILIDLGRT
     FPTHPYFSAQ LGAGQLSLYN ILKAYSLLDQ EVGYCQGLSF VAGVLLLHMS EEDAFKMLKF
     LMFDMGLRKQ YRPDMTILQI QMYQLSRLLH DYHRDLYNHL EEHEIGPSLY AAPWFLTMFA
     SQFPLGFVAR VFDMLFLQGS EAIFKVALSL LGSHKPLILQ HENLETIVDF IKSTLPNLGL
     VQMEKTISQV FEMDIAKQLQ AYEVEYHVLQ DELIDSSLND NQRLDKLEKA NSSLRKQNFD
     LLEELQVANG KIQNLEATVE LLLTNEGKLK QSILALEQER EALMNTVEKM QKK
//