ID A0A093HH72_STRCA Unreviewed; 929 AA.
AC A0A093HH72;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=Anion exchange protein {ECO:0000256|RuleBase:RU362035};
DE Flags: Fragment;
GN ORFNames=N308_12670 {ECO:0000313|EMBL:KFV81968.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV81968.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV81968.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV81968.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004554}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362035}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362035}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993, ECO:0000256|RuleBase:RU362035}.
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DR EMBL; KL206404; KFV81968.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093HH72; -.
DR STRING; 441894.ENSSCUP00000013447; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR013769; Band3_cytoplasmic_dom.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR003024; Na/HCO3_transpt.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR NCBIfam; TIGR00834; ae; 1.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF32; SODIUM-DRIVEN CHLORIDE BICARBONATE EXCHANGER; 1.
DR Pfam; PF07565; Band_3_cyto; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR PRINTS; PR01232; NAHCO3TRSPRT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU362035};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362035};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362035};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362035};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362035}.
FT TRANSMEM 386..408
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 473..496
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 503..521
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 601..619
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 639..657
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 687..706
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 727..751
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 787..809
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 859..876
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 882..899
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT DOMAIN 53..310
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 357..865
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 311..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV81968.1"
FT NON_TER 929
FT /evidence="ECO:0000313|EMBL:KFV81968.1"
SQ SEQUENCE 929 AA; 104453 MW; 012C0AC8C9F666A1 CRC64;
TPSQRVQFIL GTEDDDEEHI PHDLFTELDE ICWREGEDAE WRETARWLKF EEDVEDGGER
WSKPYVATLS LHSLFELRSC ILNGTVLLDM RANSLEEIAD MILDQQVGSG QLSEDVRHRV
HEALLKQHHH QNQKKLSNRI PIVRSFADIG KKQSEPHSMD KNGQVVSPQS APACIENKND
VSRENSTVDF SKVDLHFMKK IPPGAEASNI LVGELEFLDR AVVAFVRLSP AVLLTGLAEV
PIPTRFLFIL LGPLGKGQQY HEIGRSIATL MTDEVFHDVA YKAKDRNDLV SGIDEFLDQV
TVLPPGEWDP TIRIEPPKNV PSQEKRKIPG VPNGTAAHGD PEQPGGHSGP ELQRTGKFFG
GLILDIKRKA PFFWSDFRDA LSLQCLASFL FLYCACMSPV ITFGGLLGEA TEGRISAIES
LFGASMTGIA YSLFGGQPLT ILGSTGPVLV FEKILFKFCK EYGLSYLSLR ASIGLWTAIL
CIILVATDAS SLVCYITRFT EEAFASLICI IFIYEALEKL FHLSETYPIN MHNDLDLLTQ
YSCNCVEPEH PSNKTLQYWH DYNISASDVP WGNLTVSECK KLHGEFVGRA CGHHGPYVPD
VLFWSVILFF STVTLSSTLK QFKTSRYFPT KVRSVVSDFA VFLTILSMVL IDYAIGIPSP
KLQVPNAFKP TRDDRGWFIT PLGPNPWWTV IAAVIPALLC TILIFMDQQI TAVIINRKEH
KLKKGCGYHL DLLMVAVMLG VCSIMGLPWF VAATVLSISH VNSLKLESEC SAPGEQPKFL
GIREQRVTGL MIFVLMGSSV FLTSILKFIP MPVLYGVFLY MGASSLKGIQ LFDRIKLFWM
PAKHQPDFIY LRHVPLRKVH LFTIIQLSCL VLLWIIKVSR AAIVFPMMVL ALVFVRKLMD
FFFTKRELSW LDDLMPESKK KKLEDAEKE
//
