ID A0A093HQS1_STRCA Unreviewed; 672 AA.
AC A0A093HQS1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Interleukin-1 receptor accessory protein {ECO:0000313|EMBL:KFV85028.1};
DE Flags: Fragment;
GN ORFNames=N308_13851 {ECO:0000313|EMBL:KFV85028.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV85028.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV85028.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV85028.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC {ECO:0000256|ARBA:ARBA00009752}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL206699; KFV85028.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093HQS1; -.
DR STRING; 441894.ENSSCUP00000018606; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0004908; F:interleukin-1 receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR CDD; cd20992; Ig1_IL1R_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR004074; IL-1_rcpt_I/II-typ.
DR InterPro; IPR041416; IL-1RAcP-like_ig.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890:SF20; INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN; 1.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF18452; Ig_6; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01536; INTRLKN1R12F.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00409; IG; 3.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS50104; TIR; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Receptor {ECO:0000313|EMBL:KFV85028.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..106
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 225..331
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 386..527
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 558..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..642
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV85028.1"
FT NON_TER 672
FT /evidence="ECO:0000313|EMBL:KFV85028.1"
SQ SEQUENCE 672 AA; 76625 MW; 04A62F3359ADB783 CRC64;
AERCDDWGVD TMKQIQIYDG EPAKIKCPLF ETFLKYNYST AHSAGLTLIW YRIGQDRDLE
EPINFRLPDN RISKEKDTLW FWPALLNDTG NYTCMLRNTT YCSKVAFPLE VVAKDQHSCV
SHSIKPIEEM FYLEHANEKI ICPDIDGFYP AGVTPTVKWY KNCKLVDGFY ERYPQGSKLV
IGIVRSVFEG NYTCIVTFKD HGRTYNLTRT IKMKVVGSPN KALPPQFTSP NEKVVYELDP
GDELVLSCEV FFTFLKESRT EVWWTIDGKN TDDIMDPKIK VTQSEIIGNF EDKTITRTLM
VAKATPEDLK RNYTCYARNS RGENHSQAIV RMKVVPPKYT VELACGLGAT ILLIVVLIVV
YHVYWLEMVL FYRAHFGTDE TILDGKEYDV YVSYARNAEE EEFVLLTLRG VLENEFGYKL
CIFDRDSLPG GNTTEAVFDF IQRSRRMIVV LSPDYLTEKS ISLLEFKLGI MCQNAIATKL
IVVEYRPLQC THPSILQLKE SVSFVTWKGE KSKRSGSQFW KALRLALPLR SLNAGSGWNE
SCSSQSDISL DPIQRRRSRL KGQPDPQGAT AGALAPRGPA PVPRSKAKHR AKHFLACRCC
VTYCNGDSRL QRKHRAVAES RWETHLCKPG SGRPEEPGFQ DRSRPEPLPA QVPTLALCHY
SDLSNNNDFY VL
//
