ID   A0A093HSJ3_STRCA        Unreviewed;       635 AA.
AC   A0A093HSJ3;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=sn-1-specific diacylglycerol lipase {ECO:0000256|ARBA:ARBA00026104};
DE            EC=3.1.1.116 {ECO:0000256|ARBA:ARBA00026104};
DE   Flags: Fragment;
GN   ORFNames=N308_08858 {ECO:0000313|EMBL:KFV85658.1};
OS   Struthio camelus australis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV85658.1, ECO:0000313|Proteomes:UP000053584};
RN   [1] {ECO:0000313|EMBL:KFV85658.1, ECO:0000313|Proteomes:UP000053584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV85658.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty
CC         acid + H(+); Xref=Rhea:RHEA:33275, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17389, ChEBI:CHEBI:17815,
CC         ChEBI:CHEBI:28868; EC=3.1.1.116;
CC         Evidence={ECO:0000256|ARBA:ARBA00024531};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:33276;
CC         Evidence={ECO:0000256|ARBA:ARBA00024531};
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701}.
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DR   EMBL; KL206788; KFV85658.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093HSJ3; -.
DR   STRING; 441894.ENSSCUP00000020806; -.
DR   Proteomes; UP000053584; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd00519; Lipase_3; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002921; Fungal_lipase-like.
DR   PANTHER; PTHR45792; DIACYLGLYCEROL LIPASE HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR45792:SF2; DIACYLGLYCEROL LIPASE-BETA; 1.
DR   Pfam; PF01764; Lipase_3; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        26..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          341..473
FT                   /note="Fungal lipase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01764"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV85658.1"
FT   NON_TER         635
FT                   /evidence="ECO:0000313|EMBL:KFV85658.1"
SQ   SEQUENCE   635 AA;  70886 MW;  870822C737449C51 CRC64;
     WIGILVLYTV HKGQFDCTGG GLLHSYLLVL LILLAAIICA LSAIVCVSMR GTISNPGPRK
     SLPKLLYTRL LLYLPEFIWA IVGAVWVSDS SVHCERTVMN VIFGTVVASW IIIIFTIIGV
     VIVFDPLGGK KTVYLTDGVN RNLESSQSGQ LLYNMKSTAT RVWEKRIRLL CCCIVQDDDH
     RVAFTSIAEL FRAYFSDTDL VPSDIAAGLT LLHQEQDKME SCPKEPEEVL CHSPSSPVTD
     DLDIELENAA HYMRFAAAAY GWPYYIYTNP FTALCKLNGD CCGNRPTDSD ITGSDRRNFH
     FGSILKITGL QYRDFIHISF HNKIYEIPFF VALDHKKETI VVAVRGTLSF EDILTDLSAD
     CEDLTLEDVL ENGFVHKGIT QAATYIYRKL INDGILNQAF TIAPEYKLVI VGHSLGGGTA
     SILAIMLRNS FPTLKCFAFS PPGGLLSKSL ADYTKHFIVS VIVGKDLVAR LSMPNMEDLK
     RRIVRMVANC NKPKYQILLR GCWYEVFGGD PDNFPTELDG RNQDDLTQPL LAEESLMVHR
     SPSYNALEDE SHLNSPPQYP HLYLPGKIIH IVEESSSRRL CSSDIKYTAS WSKETVFSSI
     LISPKMITDH MPDVVLKALN SLSQEHGSCM ACQTR
//