ID A0A093HSR1_STRCA Unreviewed; 449 AA.
AC A0A093HSR1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Bifunctional apoptosis regulator {ECO:0000313|EMBL:KFV85723.1};
GN ORFNames=N308_08929 {ECO:0000313|EMBL:KFV85723.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV85723.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV85723.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV85723.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL206788; KFV85723.1; -; Genomic_DNA.
DR RefSeq; XP_009681776.1; XM_009683481.1.
DR RefSeq; XP_009681777.1; XM_009683482.1.
DR RefSeq; XP_009681778.1; XM_009683483.1.
DR RefSeq; XP_009681779.1; XM_009683484.1.
DR AlphaFoldDB; A0A093HSR1; -.
DR STRING; 441894.ENSSCUP00000021949; -.
DR Ensembl; ENSSCUT00000029034; ENSSCUP00000021949; ENSSCUG00000016054.
DR GeneID; 104149703; -.
DR KEGG; scam:104149703; -.
DR CTD; 51283; -.
DR OrthoDB; 4047619at2759; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0089720; F:caspase binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:Ensembl.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:1903895; P:negative regulation of IRE1-mediated unfolded protein response; IEA:Ensembl.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR GO; GO:0051865; P:protein autoubiquitination; IEA:Ensembl.
DR GO; GO:0070936; P:protein K48-linked ubiquitination; IEA:Ensembl.
DR GO; GO:0070534; P:protein K63-linked ubiquitination; IEA:Ensembl.
DR CDD; cd16497; RING-HC_BAR; 1.
DR CDD; cd09513; SAM_BAR; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR15898:SF21; BIFUNCTIONAL APOPTOSIS REGULATOR; 1.
DR PANTHER; PTHR15898; UNCHARACTERIZED; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..75
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 182..249
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 53140 MW; FD7D8BFE9A0B8BA3 CRC64;
MEEDETLQSE PETPRVKTHA SPEISRQISV SEFLCHCCYD ILVNPTTLNC GHSFCRHCLA
LWWVSSKKNE CPECREKWEG FPKVNILLRD VIEKLFSDAI EQRKEDIQQN SDIARSLATF
QKYGNDQIPT APNMRRINPR GGGFFSGVLT ALTCVAVVLL GYHWSSREFE DDLLVQKPVA
KWTAEEVILW LEQLGPWASH YTERFLREKV NGRLLLTLTE EDFTKEPYNI ENNNHRKAIM
TELECVKTLG VKPPQNLWEY KAVNPGKSLF LLYALKSSPR LSMLYLYLFD YAETFLPFIH
TICPMQEAEY EDTVTKLLDL KDPTWKQCRE FIVKYLFLPY QLIAEFAWDW LEVHYWTSRF
IIVNAMLLSV LELFSFWRLW SRRELKTIPH RMWRHFWKVS TQGLFVAVFW PFIPQFVCNC
LFYWALYFNP IINIDLVVKE VRRLETQVQ
//
