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Database: UniProt
Entry: A0A093HWC9_STRCA
LinkDB: A0A093HWC9_STRCA
Original site: A0A093HWC9_STRCA 
ID   A0A093HWC9_STRCA        Unreviewed;      1993 AA.
AC   A0A093HWC9;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   12-SEP-2018, entry version 23.
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808};
DE   Flags: Fragment;
GN   ORFNames=N308_00366 {ECO:0000313|EMBL:KFV83840.1};
OS   Struthio camelus australis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV83840.1, ECO:0000313|Proteomes:UP000053584};
RN   [1] {ECO:0000313|EMBL:KFV83840.1, ECO:0000313|Proteomes:UP000053584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV83840.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the
CC       entry of calcium ions into excitable cells and are also involved
CC       in a variety of calcium-dependent processes, including muscle
CC       contraction, hormone or neurotransmitter release, gene expression,
CC       cell motility, cell division and cell death.
CC       {ECO:0000256|RuleBase:RU003808}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003808};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003808}.
CC   -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit
CC       (TC 1.A.1.11) family. {ECO:0000256|RuleBase:RU003808}.
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DR   EMBL; KL206566; KFV83840.1; -; Genomic_DNA.
DR   Proteomes; UP000053584; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.350; -; 4.
DR   InterPro; IPR031688; CAC1F_C.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014873; VDCC_a1su_IQ.
DR   InterPro; IPR005451; VDCC_L_a1csu.
DR   InterPro; IPR005446; VDCC_L_a1su.
DR   InterPro; IPR002077; VDCCAlpha1.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   Pfam; PF08763; Ca_chan_IQ; 1.
DR   Pfam; PF16885; CAC1F_C; 1.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR00167; CACHANNEL.
DR   PRINTS; PR01630; LVDCCALPHA1.
DR   PRINTS; PR01635; LVDCCALPHA1C.
DR   SMART; SM01062; Ca_chan_IQ; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|RuleBase:RU003808};
KW   Calcium channel {ECO:0000256|RuleBase:RU003808};
KW   Calcium transport {ECO:0000256|RuleBase:RU003808};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053584};
KW   Ion channel {ECO:0000256|RuleBase:RU003808};
KW   Ion transport {ECO:0000256|RuleBase:RU003808};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU003808};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003808}.
FT   TRANSMEM      6     25       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     37     53       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    109    131       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    187    208       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    220    242       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    379    396       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    416    439       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    508    527       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    578    598       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    742    760       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    780    800       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    858    887       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    983   1010       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1053   1074       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1094   1114       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1135   1153       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1221   1239       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1315   1338       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1472   1506       Ca_chan_IQ. {ECO:0000259|SMART:SM01062}.
FT   COILED      616    636       {ECO:0000256|SAM:Coils}.
FT   COILED      641    661       {ECO:0000256|SAM:Coils}.
FT   COILED     1433   1453       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFV83840.1}.
FT   NON_TER    1993   1993       {ECO:0000313|EMBL:KFV83840.1}.
SQ   SEQUENCE   1993 AA;  225447 MW;  DE263CAA32C560EE CRC64;
     ERVEYLFLII FTVEAFLKVI AYGLLFHPNA YLRNGWNLLD FIIVVVGLFS AILEQATKAD
     GGNSIGGKGA GFDVKALRAF RVLRPLRLVS GVPSLQVVLN SIIKAMVPLL HIALLVLFVI
     IIYAIIGLEL FMGKMHKTCY HVQGGLIEDD PSPCAPQSAH GRQCQNGTEC KAGWEGPKHG
     ITNFDNFAFA MLTVFQCITM EGWTDVLYWV NDAIGRDWPW IYFVTLIIIG SFFVLNLVLG
     VLSGEFSKER EKAKARGDFQ KLREKQQLEE DLKGYLDWIT QAEDIDPENE DEGMDEEKPR
     NRSTPAGLPD KKKGKFAWFS HSTETHVSMP TSETESVNTD NVPGADIEGE NCGARLARYW
     RRWNRFCRRK CRAAVKSNVF YWLVIFLVFL NTLTIASEHY NQPDWLTEVQ DTANKVLLAL
     FTAEMLLKMY SLGLQAYFVS LFNRFDCFIV CGGILETILV ETKIMSPLGI SVLRCVRLLR
     IFKITRYWNS LSNLVASLLN SVRSIASLLL LLFLFIIIFS LLGMQLFGGK FNFDEMQTRR
     STFDNFPQSL LTVFQILTGE DWNSVMYDGI MAYGGPSFPG MLVCIYFIIL FICGNFILEI
     PYSVLAIWME DILFCLTAAQ KEEEEEKERK KLARTASPEK KQEIEKAAVE EETKEEKIEL
     KSITADGESP PATKVCCQPP LSLFTEEDEE EPEMPVGPRP RPMSELHLKE KAVPMPDASA
     FFIFSPNNRF RVHCHRIVND NIFTNLILFF ILLSSISLAA EDPVRHLSFR NQILGNADYV
     FTSIFTLEII LKMTAYGAFL HKGSFCRNYF NILDLLVVSV SLISFGIQSS AINVVKILRV
     LRVLRPLRAI NRAKGLKHVV QCVFVAIRTI GNIVIVTTLL QFMFACIGVQ LFKGKLYSCT
     DSSKQTAAEC RGYYITYKDG EVNQPMIQPR SWENSKFDFD NVLTAMMALF TVSTFEGWPE
     LLYRSIDSHM EDVGPIYNHR VEISIFFIIY IIIIAFFMMN IFVGFVIVTF QEQGEQEYKN
     CELDKNQRQC VEYALKARPL RRYIPKNQYQ YKVWYVVNST YFEYLMFVLI LLNTGMPIFQ
     HYGQSCMFKE AMNILNMLFT GLFTVEMVLK LIAFKPKVGA IEQEERCSKG YFSDPWNVFD
     FLIVIGSIID VILSETNVRS LFLLCCCNSC LCANGFQNAE ENSRISITFF RLFRVMRLVK
     LLSRGEGIRT LLWTFIKSFQ ALPYVALLIV MLFFIYAVIG MQVFGKIALN DTTEINRNNN
     FQTFPQAVLL LFRCATGEAW QEIMLACLPD KKCDPESEPA NSTEADHSCG SSFAVFYFIS
     FYMLCAFLII NLFVAVIMDN FDYLTRDWSI LGPHHLDEFK RIWAEYDPEA KGRIKHLDVV
     TLLRRIQPPL GFGKLCPHRV ACKRLVSMNM PLNSDGTVMF NATLFALVRT ALRIKTEGNL
     EQANEELRAI IKKIWKRTSM KLLDQVVPPA GDDEVTVGKF YATFLIQEYF RKFKKRKEQG
     LVGKPSQRNA LSLQAGLRTL HDIGPEIRRA ISGDLTAEEE LDKAMKEAVS AASEDDIFRR
     AGGLFGNHVS YYQSDGRSAF PQTFTTQRPL HINKSGNNQG DTESPSHEKL VDSTFTPSSY
     SSSGSNANIN NANNTALCRF PSPPSYPSTV STVEGHGTPL SPTIRVQEAP WKLPSKRDSQ
     LAIVCQEEVS QDETYDENLN EDIEYCSEPS LISTEMLSYH DDENRQLTPP ENNKGEDTRH
     SPKKGFLCSS SLGRRASFHL ECLKRQKNQG VDVSQKTVLP LHLVHHQALA VAGLSPLLQR
     SHSPTTFSRL CATPPATPCS RGWPQQTIPT LRLDGAESSE KLNSSFPSIH CSSRYPDNSG
     CSSPRRARPV SLTVPSQTGG SNRQFHGSAG SLVEAVLISE GLMQFAQDPK FIEVTTQELA
     DACDMTIEEM ENAADNILNG NSKQSPNGNL LPFVNCRDPG QDSAGEEEEE VQNPDCRKSQ
     EELKDSRIYI SSL
//
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