ID A0A093HZ50_STRCA Unreviewed; 1381 AA.
AC A0A093HZ50;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
DE Flags: Fragment;
GN ORFNames=N308_15405 {ECO:0000313|EMBL:KFV88038.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV88038.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV88038.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV88038.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|RuleBase:RU004279};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|ARBA:ARBA00006460, ECO:0000256|RuleBase:RU004279}.
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DR EMBL; KL206988; KFV88038.1; -; Genomic_DNA.
DR STRING; 441894.ENSSCUP00000019932; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0031981; C:nuclear lumen; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02736; RNAP_III_Rpc1_C; 1.
DR CDD; cd02583; RNAP_III_RPC1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR035698; RNAP_III_Rpc1_C.
DR InterPro; IPR035697; RNAP_III_RPC1_N.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF32; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 233..544
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV88038.1"
FT NON_TER 1381
FT /evidence="ECO:0000313|EMBL:KFV88038.1"
SQ SEQUENCE 1381 AA; 154684 MW; E03D9F710CE1E5B1 CRC64;
SHICFGMKSP EEMRQQAHIQ VVSKNLYSQD NHHSPLQYGV LDHRMGTSEK DRPCETCGKN
LADCLGHYGY IDLELPCFHV GYFKAVIGIL QMICKTCCRI MLSLEEKKQF LDYLKRPGLT
YLQKRGLKKK VSEKCRKKTT CPYCGAFNGT VKKCGLLKII HEKYKTNKKV VDPIVSTFLQ
SFETAIEHNK EVESLLGRAQ ENLNPLVVLN LFKRIRAEDI PLLLMNPEAG KPSDLILTRL
LVPPLCIRPS VVSDLKSGTN EDDLTMKLTE IIFLNDVIKK HRISGAKTQM IMEDWDFLQL
QCALYINSEL SGIPLNMAPK KWTRGFVQRL KGKQGRFRGN LSGKRVDFSG RTVISPDPNL
RIDEVAVPIH VAKILTFPEK ANFMQQVNKA NINFMRKLVR NGPDVHPGAN FIQQRHTQMK
RFLKYGNREK MAQELKFGDI VERHLIDGDI VLFNRQPSLH KLSIMAHIAR VKPHRTFRFN
ECVCTPYNAD FDGDEMNLHL PQTEEAKAEA LVLMGTKANL VTPRNGEPLI AAIQDFLTGA
YLLTLKDTFF DRAKACQIIA SILVGKDEKI KVRLPPPAIL KPVTLWTGKQ VFSLILKPSD
DCPVKANLRT KGKQYCGKGE DLCFNDSYVT IQNSELMSGS MDKGTLGSGS KNNIFYILLR
DWGQVEAADA MSRLARLAPV YLSNRGFSIG IGDVTPGQGL LKAKYELLNA GYKKCDEYIE
ALNTGKLQQQ PGCTAEETLE ALILKELSVI RDHAGSACLR ELDKSNSPLI MALCGSKGSF
INISQMIACV GQQAISGSRV PDGFENRSLP HFEKHSKLPA AKGFVANSFY SGLTPTEFFF
HTMAGREGLV DTAVKTAETG YMQRRLVKSL EDLCSQYDLT VRSSTGDIIQ FIYGGDGLDP
AAMEGKDEPL EFKRVLDNIR AVYPCRNEPA LSKNELVLTS ESIMKKNEFL CCRDSFLQEI
KKFIKGVSEK IKKTRDKYGI NDNGTTEPRV LYQLDRITPT QLEKFLETCR DKYMRAQMEP
GSAVGALCAQ SIGEPGTQMT LKTFHFAGVA SMNITLGVPR IKEIINASKA ISTPIITAQL
DKDDDPDFAR LVKGRIEKTL LGEISEYIEE VFLPDDCFIL VKLSLERIRL LRLEVNAETV
RYSICISKLR VKPGDVAVHG EAVVCVTPRE NSKSSMYYVL QSLKEELPKV VVQGIPEVSR
AVIHIDEQSG KEKYKLLVEG DNLRAVMATH GVKGTKTSSN NTYEVEKTLG IEAARTTIIN
EIQYTMVNHG MSIDRRHVML LSDLMTYKGE VLGITRFGLA KMKESVLMLA SFEKTADHLF
DAAYFGQKDS VCGVSECIIM GIPMNIGTGL FKLLHKADKE SAPPRRPLIF DNNEFHIPIV
T
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