ID A0A093I013_STRCA Unreviewed; 673 AA.
AC A0A093I013;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Proprotein convertase subtilisin/kexin type 6 {ECO:0000313|EMBL:KFV84567.1};
DE Flags: Fragment;
GN ORFNames=N308_02618 {ECO:0000313|EMBL:KFV84567.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV84567.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV84567.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV84567.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; KL206666; KFV84567.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093I013; -.
DR STRING; 441894.ENSSCUP00000017937; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00064; FU; 3.
DR CDD; cd04059; Peptidases_S8_Protein_convertases_Kexins_Furin-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR034182; Kexin/furin.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR010909; PLAC.
DR InterPro; IPR043601; Rspo_Fu-CRD_dom.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR PANTHER; PTHR42884:SF8; PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 6; 1.
DR Pfam; PF15913; Furin-like_2; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR SMART; SM00261; FU; 4.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 221..361
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT DOMAIN 635..673
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV84567.1"
FT NON_TER 673
FT /evidence="ECO:0000313|EMBL:KFV84567.1"
SQ SEQUENCE 673 AA; 73740 MW; 0D10950324C4BC96 CRC64;
GIRMLDGDVT DVVEAKSLGI RPDYIDIYSA SWGPDDDGKT VDGPGLLAKQ AFEHGIKKGR
RGLGSIFVWA SGNGGREGDY CSCDGYTNSI YTISVSSTTE NGYKPWYLEE CASTLATTYS
SGAFYERKIV TADLRHRCTD GHTGTSVSAP MVAGIIALAL EANPLLTWRD VQHLLVKTSR
PVHLRAADWK TNGAGHKVSH LYGFGLVDAE AIVMEAKKWK SVPPQHVCVG SLDRVPKYIR
ADHVVRATTL ASACADHYDQ HVVYLEHVVV RVTISHPRRG DLQISLISPA GTRSQLLARR
VFDHSNEGFK GWEFMTVHCW GEKAAGEWTL EIHDTPSQVR NPAAQGKLKE WSLLFYGTAE
HPYNTLSSHH SRSRMLEISA SEMEPSKVAL LQSQMEIVEE EEEYTGPCHP ECGDQGCDGP
NADQCLNCIH YSLGSMKTGR MCVSSCPSGF FGDKGARRCR RCYKGCESCL GRGPNQCTAC
KRSLYHHQEM NTCVVLCPPG FYSEERQKRC LKCHQSCKKC VGEPDKCTAC KDGFSSGSFA
SWVPSLLFLP FGEAARGQCF ELGEVDCAAC APEAPVPEWS CVPACPEGFY PGESPGLPHQ
VCKRCDDHCL ACEGSSGNCV KCKEGFSLLS GSCVTNETCT NADKTFCEMV KSNKLCEKKL
FVQFCCQTCL MAG
//
