ID A0A093I1T9_FULGA Unreviewed; 1292 AA.
AC A0A093I1T9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|EMBL:KFV96468.1};
DE Flags: Fragment;
GN ORFNames=N327_03642 {ECO:0000313|EMBL:KFV96468.1};
OS Fulmarus glacialis (Northern fulmar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Procellariiformes; Procellariidae;
OC Fulmarus.
OX NCBI_TaxID=30455 {ECO:0000313|EMBL:KFV96468.1, ECO:0000313|Proteomes:UP000053806};
RN [1] {ECO:0000313|EMBL:KFV96468.1, ECO:0000313|Proteomes:UP000053806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N327 {ECO:0000313|EMBL:KFV96468.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK584888; KFV96468.1; -; Genomic_DNA.
DR Proteomes; UP000053806; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04385; RhoGAP_ARAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 4.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR037858; RhoGAP_ARAP.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45899:SF4; ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR45899; RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 4.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 4.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 3.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053806};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 249..299
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 423..514
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 705..803
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 781..960
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 989..1101
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 1100..1202
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1267..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1267..1282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV96468.1"
FT NON_TER 1292
FT /evidence="ECO:0000313|EMBL:KFV96468.1"
SQ SEQUENCE 1292 AA; 144292 MW; 6F928803361218F2 CRC64;
QKDPAPPLVK PVPKPRTVFP RSKPEQGLAP APPARTTVPA HSPGSDGAPA AFVVLEGFVP
GESSTDLESP AVAMGMGASR LRGRESAREE TRHPPALDHG QTLEASEKSP PSIPSVPPRH
SHRVLVAEPS PGSTPEGAAS SPCKPDGKTM WKNPAGSHPI LAAVTPLLFS SSRGWPGGGL
PPVPQRPTGK PGERPQGTGA QRGPLGVPKE GGDGDTCTPC LSPRVWRCPT GRAKGGNPAC
GSFQEPYSKG VIPLSVIEMA RSTKDNKFQV FTSHRIFVFR AENEAQRNEW CSTLQKKVTD
QRLVGSRPRP ANTAHCQKSG TLELKGQKSK VFAALSLPEM WLYKSEQFFK MGIGICFIEM
RGSTIREAKN RSFELITPFK IFRYPRRLGG TRWGEQPGAG PGCWVLAGVS VRLGCRFPWQ
DQGVLTLLLP AGQHRSLGSN ISKVQSLKLD TSVWSNEIVQ LFIVLGNDRA NRFWAARLPA
AEALYPDASA EQRRDFISRK YREGRYRLPH PHYATQEDVL QALCAAVAGP ALLKTILQFF
SSSEAGLAAD PTAREVALGA DLCPRTRELG PEGVYNEITQ PVTHSGYLYR ATAPPKLPGT
KKNKEDFQRT WCSLERALLF FETEKCTEPL GHIESGDLIS LGVSKAQALA SSSPTERFRF
TLEMFLTGEK VQQLGTDGPE TLQAWASAIG KWFTPVSCHC LLGYEFQRVG QLRYKCMLNP
ERWQQAFFIL QKAHLFICPA EDDGAEDSIN LRRLQELSLV PPTETPEKKE LLILVEMGRT
FYLQGLSRAD SAAWYADIQA SAGGRGLRHE GIYRKNGAKS RIKVLMEEFR RDARNVKLRI
NDNFIEDVTD VLKRFFRELE DPVFTLELHP QWKEAAEISS KPQRLERYKE LIHRLPRLNH
KTLAALIGHL YRVQKCADLN QMSTKNLSLL FAPSLFQTDG KGEHEVKVME DLIDNYVSIF
NIDEDQVSQM DLENSLITTW KDTQLSQAGD LIIEVYLEQK LPDCCITLKV SPTMTAEELT
NQVLEMRNVA ASLDIWLTFE ALENGELGER GGDGMGGCSR RGQAGEEEWC KLPEPSAAYL
LVRKVPIREG SCLFTGVKRE TPKCGLLKCR EEPPKLLGNK FQERYFVIRD RRLLLLKEKR
SAKPEREWPL DTAKVYMGIR KKLKPPAQWG FTLTLDKQQL YLVCSGQAEL WDWTTSILKA
QHDDLRPVIM RRRSSSDLAK QKFGTMPLVP LHGDSTDATM LSANQTLRRL HTRRTLSMFF
PMKMHQDSLE EQQEKEADTD PVYEEVGNFP EL
//
