ID A0A093I4N6_STRCA Unreviewed; 221 AA.
AC A0A093I4N6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Hairy/enhancer-of-split related with YRPW motif protein 1 {ECO:0000256|ARBA:ARBA00040633};
DE Flags: Fragment;
GN ORFNames=N308_13805 {ECO:0000313|EMBL:KFV88866.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV88866.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV88866.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV88866.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HEY family. {ECO:0000256|ARBA:ARBA00038262}.
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DR EMBL; KL207004; KFV88866.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093I4N6; -.
DR STRING; 441894.ENSSCUP00000021416; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 6.10.250.980; -; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR003650; Orange_dom.
DR PANTHER; PTHR10985; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED; 1.
DR PANTHER; PTHR10985:SF78; HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 1; 1.
DR Pfam; PF07527; Hairy_orange; 1.
DR SMART; SM00511; ORANGE; 1.
DR SUPFAM; SSF158457; Orange domain-like; 1.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS51054; ORANGE; 1.
PE 3: Inferred from homology;
KW Notch signaling pathway {ECO:0000256|ARBA:ARBA00022976};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 1..21
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 43..75
FT /note="Orange"
FT /evidence="ECO:0000259|PROSITE:PS51054"
FT REGION 112..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV88866.1"
FT NON_TER 221
FT /evidence="ECO:0000313|EMBL:KFV88866.1"
SQ SEQUENCE 221 AA; 23603 MW; D33889EF815B257A CRC64;
GSAKLEKAEI LQMTVDHLKM LHTAGGKGYF DAHALAMDYR SLGFRECLAE VARYLSIIEG
LDASDPLRVR LVSHLNNYAS QREAASSAHT GIGHIPWGSA FGHHPHISHP LLLPQNGHCN
TSTTASSTEP HHQSRIAAPH AETSSLRVPP NGSVGPVLPV VTSTSKLSPP LLSSMASLSA
FPFSFSSFHL LTPNVLSPSA PTQSANFGKP YRPWGTEIGA F
//
