ID   A0A093I7Z8_EURHL        Unreviewed;       412 AA.
AC   A0A093I7Z8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Ras-GEF domain-containing family member 1A {ECO:0000313|EMBL:KFV97752.1};
DE   Flags: Fragment;
GN   ORFNames=N326_12945 {ECO:0000313|EMBL:KFV97752.1};
OS   Eurypyga helias (Sunbittern) (Ardea helias).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Eurypygimorphae; Eurypygiformes;
OC   Eurypygidae; Eurypyga.
OX   NCBI_TaxID=54383 {ECO:0000313|EMBL:KFV97752.1, ECO:0000313|Proteomes:UP000054232};
RN   [1] {ECO:0000313|EMBL:KFV97752.1, ECO:0000313|Proteomes:UP000054232}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N326 {ECO:0000313|EMBL:KFV97752.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK555270; KFV97752.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093I7Z8; -.
DR   Proteomes; UP000054232; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd06224; REM; 1.
DR   Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR   Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR   InterPro; IPR008937; Ras-like_GEF.
DR   InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR   InterPro; IPR023578; Ras_GEF_dom_sf.
DR   InterPro; IPR001895; RASGEF_cat_dom.
DR   InterPro; IPR036964; RASGEF_cat_dom_sf.
DR   PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR23113:SF172; RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1A; 1.
DR   Pfam; PF00617; RasGEF; 1.
DR   Pfam; PF00618; RasGEF_N; 1.
DR   SMART; SM00147; RasGEF; 1.
DR   SUPFAM; SSF48366; Ras GEF; 1.
DR   PROSITE; PS50009; RASGEF_CAT; 1.
DR   PROSITE; PS50212; RASGEF_NTER; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW   ECO:0000256|PROSITE-ProRule:PRU00168};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054232}.
FT   DOMAIN          1..108
FT                   /note="N-terminal Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50212"
FT   DOMAIN          152..399
FT                   /note="Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50009"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV97752.1"
FT   NON_TER         412
FT                   /evidence="ECO:0000313|EMBL:KFV97752.1"
SQ   SEQUENCE   412 AA;  48159 MW;  F1DD0DDB67277709 CRC64;
     PQRTYIFTVL LSSRVFIHPH ELLAKVGQLC IKQKQQLETG TEAEKAKLKS FAAKIIQLLK
     EWTETFPYDF QDEKSMKELK EIAHRITQCD EENGTVKKII SQMTQNLLMA LSARSQYQEI
     REKFRQPVTD KGTILKTKPQ STQKDILSVC CDPLILAQQL TYIELERVNN IYPEDLMQIV
     SHMDSLDNHK CRGDVTKTYN LEAYDNWFNC LSMLVATEIC RIVKKKQRTR MVEFFIDVAR
     ECFNIGNFNS MMAIISGMNL SPVARLKKTW SKVKTAKFDV LEHHMDPSSN FCNYRTALQG
     AAQRSQTANS NREKIVIPVF NLFIKDIYFL HKIHMNRLPN GQINFKKFWE ISRQIHDFLT
     WKQVECPFEK DKKIQSYLLT APIYSEEALF IASFESEGPE NHMEKDSWKT LR
//