ID A0A093IC54_DRYPU Unreviewed; 516 AA.
AC A0A093IC54;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Caspase-10 {ECO:0000313|EMBL:KFV64296.1};
DE Flags: Fragment;
GN ORFNames=N307_07765 {ECO:0000313|EMBL:KFV64296.1};
OS Dryobates pubescens (Downy woodpecker) (Picoides pubescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates.
OX NCBI_TaxID=118200 {ECO:0000313|EMBL:KFV64296.1, ECO:0000313|Proteomes:UP000053875};
RN [1] {ECO:0000313|EMBL:KFV64296.1, ECO:0000313|Proteomes:UP000053875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N307 {ECO:0000313|EMBL:KFV64296.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C14A family.
CC {ECO:0000256|ARBA:ARBA00010134, ECO:0000256|RuleBase:RU003971}.
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DR EMBL; KL215353; KFV64296.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093IC54; -.
DR STRING; 118200.A0A093IC54; -.
DR MEROPS; C14.011; -.
DR Proteomes; UP000053875; Unassembled WGS sequence.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd00032; CASc; 1.
DR Gene3D; 3.40.50.1460; -; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR033139; Caspase_cys_AS.
DR InterPro; IPR016129; Caspase_his_AS.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001875; DED_dom.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR002138; Pept_C14_p10.
DR InterPro; IPR001309; Pept_C14_p20.
DR InterPro; IPR015917; Pept_C14A.
DR PANTHER; PTHR48169:SF5; CASPASE 10; 1.
DR PANTHER; PTHR48169; DED DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01335; DED; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR PRINTS; PR00376; IL1BCENZYME.
DR SMART; SM00115; CASc; 1.
DR SMART; SM00031; DED; 2.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR SUPFAM; SSF47986; DEATH domain; 2.
DR PROSITE; PS01122; CASPASE_CYS; 1.
DR PROSITE; PS01121; CASPASE_HIS; 1.
DR PROSITE; PS50207; CASPASE_P10; 1.
DR PROSITE; PS50208; CASPASE_P20; 1.
DR PROSITE; PS50168; DED; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000053875};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 11..89
FT /note="DED"
FT /evidence="ECO:0000259|PROSITE:PS50168"
FT DOMAIN 271..395
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
FT DOMAIN 420..507
FT /note="Caspase family p10"
FT /evidence="ECO:0000259|PROSITE:PS50207"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV64296.1"
FT NON_TER 516
FT /evidence="ECO:0000313|EMBL:KFV64296.1"
SQ SEQUENCE 516 AA; 58847 MW; D7734D573981F0AF CRC64;
SSNMEEDVSL KFRQQLLLID QNLVAEDVAA LKFFCTDLLP SRKLESVKSA VDIFQLLMAE
EYLNEGDTFL LAELLYRIKC HSLLKKLGYT KEKVEECLHE KGRVSPYRQM LYELSENIRT
ITILLSPFGY QSTLDVLILL EKQGLVSDNN VQMLEDICME VSPNLVKTVN CYRTKVSLPQ
QESTFPVKES SLSHSGDIRV FASPLVHWNT YCLLGHRDSH NSIVLLGYGL EKYSGHLEIK
SDRGVVSKDV AKRIKESKFL KMTTYKMDGP HRGFCLVINN VNFDGSLQER KGSCKDAEEL
KRVFTWLGLD VRTYKDQTAQ QIMNLMQTWQ HFPDHKDRDC FICCILSHGE SGAVYGKDEE
LVSIRTIMSY FTARQCPQLA EKPKLFFIQA CQGKAVQCPV YVEPDARVPG LSFMQHSVSP
SESIPEEADF LLGMATIDGY VSFRHVQQGT WYIQALCSKL QLLVPRGEDI LSILTEVNED
VGRRVDRLGT KKQMPQPAYT LRRKFIFPIP KDPPPS
//
