ID A0A093IGR0_EURHL Unreviewed; 1078 AA.
AC A0A093IGR0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Leukemia inhibitory factor receptor {ECO:0000313|EMBL:KFV98796.1};
DE Flags: Fragment;
GN ORFNames=N326_09262 {ECO:0000313|EMBL:KFV98796.1};
OS Eurypyga helias (Sunbittern) (Ardea helias).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Eurypygiformes;
OC Eurypygidae; Eurypyga.
OX NCBI_TaxID=54383 {ECO:0000313|EMBL:KFV98796.1, ECO:0000313|Proteomes:UP000054232};
RN [1] {ECO:0000313|EMBL:KFV98796.1, ECO:0000313|Proteomes:UP000054232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N326 {ECO:0000313|EMBL:KFV98796.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00008921}.
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DR EMBL; KK557023; KFV98796.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093IGR0; -.
DR Proteomes; UP000054232; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR003529; Hematopoietin_rcpt_Gp130_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR048497; LIF-R-like_Ig-like.
DR InterPro; IPR040817; LIFR_D2.
DR InterPro; IPR040901; LIFR_N.
DR PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23036:SF105; LEUKEMIA INHIBITORY FACTOR RECEPTOR; 1.
DR Pfam; PF21177; LIF-R_Ig-like; 1.
DR Pfam; PF17971; LIFR_D2; 1.
DR Pfam; PF18207; LIFR_N; 1.
DR SMART; SM00060; FN3; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS01353; HEMATOPO_REC_L_F2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KFV98796.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054232};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 810..835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 410..509
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 511..605
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 700..809
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 994..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1011..1046
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV98796.1"
FT NON_TER 1078
FT /evidence="ECO:0000313|EMBL:KFV98796.1"
SQ SEQUENCE 1078 AA; 120687 MW; EE43E4F31C77DAFA CRC64;
ILCLRSLIYS QEIGSLGHPQ NLKCVTHNLR KMICSWDVSS KGRHGQTDFC YTTNDLPPPV
CFKTKEKRVE IPVPESSTTV TITTNSISGT AFATKEFEIH QKDISFVPLT PHILSLTPDF
STSTINLKWS DNGSVLPYGL DAFWQIQILR KETMEKVTQV TYYSKLTRED IILSWNWRSD
MPLECTSHYV KIRCYINVTQ FLGPKDWSDW SPVEEFPGKD IEPSGNRVFP QDTVVAVGSD
VTICCVHEEG QPIQQITYGS EIYPMIHLSS RSSAIRVLNA SASDTSGTNV VCMLSEEDMD
GTVLFVGYAP DIPQNLSCET SNFLIIKCTW KPGRPSGLYG KRRTKYSLFE RISGKNVSCE
VNEMNRERVC GFPVLVDQKT YDFILGVSNP IGQTESSLFI DLTQRVHPKT PEKLTVSGNS
STSVHLRWFI NGSFAEIRLL CQIEVNSGHS ERKLHNVSMP GRKFSTYTAQ LNTLHSYTKY
QFRVRCSAAD HFWRWSDWSR IEEHTTLEAP PARGPDIWRE RSPSGKSLKI FWKPLSLSEA
NGKILSHEVA CYLLETPLEY KEVTEPSNST EIKLGKNDCV ISVVAKNHAG SSPPSRITSV
ELPSDNVKTD RAVAMGNGIY ISWNSYPNVT CGYIVKWCHS SGSEPCSMDW QKFPSNVTDA
VIKSALFRPG VRYDFSLYGC KSSGYQLLKN ITGYMKELPP KRAPNFTVEE TSSDSILVKW
EDIPIEDCQG FLEGYRLSFA KGEKDALKPR LSESGNPELK IKNITDLTKK SLKILDLQGK
TSYQLDLQAY TAGGLSPPNS LYVVTKEDSV GLIIAILIPV AVVVLLGVVA SIFCYRKREW
IKETFYPEIP NPENSKALQF QKNICEGNKT LKTLEMNPCT PSSVEVVETR SAAPKIEDTE
MMSPAADTIV PEDGSDSETE NHVVVSYCPP IIEEEISNPP MDEPVGSSQV VYIDIQSMYQ
PQIKPEEEPE IDIVTTAGYK PQMQLPISAL KIESRSPAEE ELDKTAGYRP QANANAWNMD
TPDSPGSVES NNESASFGSP CSINSRQFLL PPKDDEDSPK PSNIGWSFTH FFHNKQND
//
