ID A0A093J2Z8_FULGA Unreviewed; 769 AA.
AC A0A093J2Z8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
DE Flags: Fragment;
GN ORFNames=N327_05021 {ECO:0000313|EMBL:KFW06272.1};
OS Fulmarus glacialis (Northern fulmar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Procellariiformes; Procellariidae;
OC Fulmarus.
OX NCBI_TaxID=30455 {ECO:0000313|EMBL:KFW06272.1, ECO:0000313|Proteomes:UP000053806};
RN [1] {ECO:0000313|EMBL:KFW06272.1, ECO:0000313|Proteomes:UP000053806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N327 {ECO:0000313|EMBL:KFW06272.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|RuleBase:RU361221}.
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DR EMBL; KK601192; KFW06272.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093J2Z8; -.
DR Proteomes; UP000053806; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd04591; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd03685; ClC_6_like; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR002249; Cl_channel-7.
DR PANTHER; PTHR11689; CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER; 1.
DR PANTHER; PTHR11689:SF166; H(+)_CL(-) EXCHANGE TRANSPORTER 7; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR PRINTS; PR01118; CLCHANNEL7.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000053806};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 85..106
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 134..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 185..202
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 246..268
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 280..303
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 335..357
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 446..465
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 471..493
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 505..529
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 535..556
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 699..763
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW06272.1"
FT NON_TER 769
FT /evidence="ECO:0000313|EMBL:KFW06272.1"
SQ SEQUENCE 769 AA; 84937 MW; E35A33E9576A0641 CRC64;
QLTPSSFLRI GQLSNVDLNE DIRELVRDGA PEPPRQHPNE IPHNEKLLSL KYESLDYDNS
ENQLFLEEER RINHTAFRTV EIKRWVICAM IGILTGLVAC FIDIVVENLA GLKYRVVKGN
IDKFTEKGGL SFSLLLWATL NASVVMVGSV IVAFIEPVAA GSGIPQIKCY LNGVKIPHVV
RLKTLVIKVC GVILSVVGGL AVGKEGPMIH SGAVIAAGIS QGRSTSLKRD FKIFEYFRRD
TEKRDFVSAG AAAGVSAAFG APVGGVLFSL EEGASFWNQF LTWRIFFASM ISTFTLNSVL
SVYHGNAWDL SSPGLINFGR FDNEKMGYTI QEIPIFIFMG VVGGILGALF NALNYWLTMF
RIRYIHRPCL QVVEAMLVAA VTATVGFVMI YCSRDCQPIQ GSTVAYPLQL FCADGEYNSM
ATAFFNTPEK SVVNLFHDPP GSYNPMTLGM FTLMYFFLAC WTYGLTVSAG VFIPSLLIGA
AWGRLFGISL SYLTKGSIWA DPGKYALMGA AAQLGGIVRM TLSLTVIMME ATGNVTYGFP
IMLVLMTAKI VGDYFVEGLY DMHIQLQSVP FLHWEAPVTS HSLTAREVMS TPVTCLRRIE
RVGTVVDILS DTSSNHNGFP VVESNPDATQ VGMQLGCCMT VPDGLSPPQV FVERANLSLV
QRRLKLKDFR DAYPRFPPIQ SIHVSQDERE CMIDLSEFMN PSPYTVPQEA SLPRVFKLFR
ALGLRQLCMP AWGCTLSLSW QVVGMVTRKD LARYRLGKEG LEELSLAQT
//
