ID A0A093N985_PYGAD Unreviewed; 686 AA.
AC A0A093N985;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Transient receptor potential cation channel subfamily V member 5 {ECO:0000313|EMBL:KFW61558.1};
DE Flags: Fragment;
GN ORFNames=AS28_01375 {ECO:0000313|EMBL:KFW61558.1};
OS Pygoscelis adeliae (Adelie penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae; Pygoscelis.
OX NCBI_TaxID=9238 {ECO:0000313|EMBL:KFW61558.1, ECO:0000313|Proteomes:UP000054081};
RN [1] {ECO:0000313|EMBL:KFW61558.1, ECO:0000313|Proteomes:UP000054081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS28 {ECO:0000313|EMBL:KFW61558.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL224604; KFW61558.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093N985; -.
DR STRING; 9238.A0A093N985; -.
DR Proteomes; UP000054081; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR CDD; cd22296; CBD_TRPV5_C; 1.
DR CDD; cd22192; TRPV5-6; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR024862; TRPV.
DR InterPro; IPR008346; TRPV5.
DR InterPro; IPR008344; TRPV5/TRPV6.
DR NCBIfam; TIGR00870; trp; 1.
DR PANTHER; PTHR10582:SF25; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6; 1.
DR PANTHER; PTHR10582; TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01415; ANKYRIN.
DR PRINTS; PR01765; ECACCHANNEL.
DR PRINTS; PR01767; ECACCHANNEL2.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KFW61558.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054081};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 292..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 79..111
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 126..158
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 293..551
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW61558.1"
FT NON_TER 686
FT /evidence="ECO:0000313|EMBL:KFW61558.1"
SQ SEQUENCE 686 AA; 78695 MW; 37372345E8247674 CRC64;
LFLDYRIWES PLLQAAKENN LPAIRKLLTD GTCDFYQRGA VGETALHVAA LYDNVEAAVT
LMEAAPELVN ERMTSELYEG QTALHIAAVN QNITLVKALL KRGANACTAR ATGHFFRRSS
QNLLYFGEHV LSFAACVGNE EIVQLLIENG ADIRAQDYLG NTVLHILVLQ PNKTFACHMY
SLILSYDRKK EGPGSLELIP NNEGLTPFKL AGVEGNTVMF QYLMQKRKHN LWSFGPLTTV
LYDLTEIDSW AEDQSFLELI VSTKKREARQ ILDLTPVKEL VSLKWNMYGR PYFCFLALFY
ILYMVCFTMC CVYRPLKPRI GNKTSSRDNT VYIQKMLQES YMTYEDELRL VGELITVIGA
VVILILEIPD ILRVGAAKYF GQTILGGPFH IIVITYACMI LVTMVMRLTS TTGEVVPMSF
ALVLGWCNVM YFARGFQMLG PFTIMIQKMI FGDLMRFCWL MAVVILGFAS AFYIIFQTEN
PENLGQFYNY PMSLFTTFEL FLTIIDGPAN YDVDLPFMYS VVYFAFAIIA TLLMLNLLIA
MMGDTHWRVA HERDELWRAQ VVATTVMLER KLPRCLWPRS GICGREYGLG DRWYLRVEDR
VDPNKHKVMR YTEAFKAQDR DNYDKGLEKM EINRNILYKK ELSGLSLSRS TSRTSSHRGW
EILRRNTFHQ LRGEVSHTME EEVYDV
//
