ID A0A093NHP2_PYGAD Unreviewed; 879 AA.
AC A0A093NHP2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Laminin subunit alpha-2 {ECO:0000313|EMBL:KFW63636.1};
DE Flags: Fragment;
GN ORFNames=AS28_03758 {ECO:0000313|EMBL:KFW63636.1};
OS Pygoscelis adeliae (Adelie penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae; Pygoscelis.
OX NCBI_TaxID=9238 {ECO:0000313|EMBL:KFW63636.1, ECO:0000313|Proteomes:UP000054081};
RN [1] {ECO:0000313|EMBL:KFW63636.1, ECO:0000313|Proteomes:UP000054081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS28 {ECO:0000313|EMBL:KFW63636.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; KL224787; KFW63636.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093NHP2; -.
DR STRING; 9238.A0A093NHP2; -.
DR Proteomes; UP000054081; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00055; EGF_Lam; 6.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF291; LAMININ SUBUNIT ALPHA-2; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00053; Laminin_EGF; 8.
DR Pfam; PF00055; Laminin_N; 1.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00180; EGF_Lam; 7.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01248; EGF_LAM_1; 3.
DR PROSITE; PS50027; EGF_LAM_2; 5.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022869};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000054081};
KW Secreted {ECO:0000256|ARBA:ARBA00022869}.
FT DOMAIN 1..249
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 377..431
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 432..480
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 501..686
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DOMAIN 720..769
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 770..827
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 828..879
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DISULFID 377..389
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 407..416
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 451..460
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 739..748
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 798..807
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 852..861
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 864..878
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW63636.1"
FT NON_TER 879
FT /evidence="ECO:0000313|EMBL:KFW63636.1"
SQ SEQUENCE 879 AA; 97032 MW; 37B7C6B23B0C63AE CRC64;
GLFPAVLNLA TNALITTNAT CGEKGREMYC KLVEHVPGQP ARNPQCRICD QRSRVPHQRH
PITNAIDGKN TWWQSPSIQN GIEYHYVTIT LDLQQIFQIA YVIVKAANSP RPGNWILERS
LDGVDYQPWQ YYAITDSECL TRYNIHPRPG TPSYVKDDEV ICTSYYSKIH PLENGEIHTS
LINGRPSADD PSRVLLEFTS ARFIRLRFQR IRTLNADLMM FAHKDPNEID PIVTRRYYYS
VKDISVGGMC ICSGHAKACP PDPATNKSVC QCEHNTCGET CDRCCPGFNQ KPWHAGTFLV
KHECEPCNCH GKTEVCYYDQ DIADRNQSLN VRGEYIGGGV CVNCTSHTGG INCETCVDGY
FRPKGVLPDS PDPCQPCSCD PNGSLHDTCV KDEKHAEGDM LPGFCHCKTG YAGESCNRCA
LGYTGYPECL PCNCSLKGSV NVDPCIGPCV CKEHVEGENC DRCKPGFFNL QRNNPKGCEE
CFCSGKTNVC THSHFTYRSM EDMNGWYLTG LLGLTRVTPR QKRFDGHQQF SISNVAARKV
LPQTYYWSAP SSYLGNKVAA AGGHLKFTVS YDFTEEEETV QLMVQSDVII EGGDLRISTP
KGGIHLQPSE EHTEEIVLKP ESFSVHGTDV PVSRREFMTI LANVKRILIR ATYSYGMNAI
YRLRSVSIEA ADHTSTGRKV ASAVELCDCP PGYDGTSCES CWPRHRRVNG TIFGGVCAPC
TCFGHAELCD DITGECLDCK HNTGGSYCDR CLPGFYGEPT KGTAEDCQLC ACPLNIPSNN
FSPTCHFDRS HGLICDECPA GYVGPRCERC AEGYFGQPLI PGGSCQPCQC NDNLDFSIPG
SCDSLSGACL ICKPGTTGQY CERCADGYFG DALDARNCQ
//
