ID A0A093P8L6_PYGAD Unreviewed; 416 AA.
AC A0A093P8L6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Rho GTPase-activating protein 8 {ECO:0000313|EMBL:KFW73283.1};
DE Flags: Fragment;
GN ORFNames=AS28_08974 {ECO:0000313|EMBL:KFW73283.1};
OS Pygoscelis adeliae (Adelie penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae; Pygoscelis.
OX NCBI_TaxID=9238 {ECO:0000313|EMBL:KFW73283.1, ECO:0000313|Proteomes:UP000054081};
RN [1] {ECO:0000313|EMBL:KFW73283.1, ECO:0000313|Proteomes:UP000054081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS28 {ECO:0000313|EMBL:KFW73283.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL225530; KFW73283.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093P8L6; -.
DR Proteomes; UP000054081; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04404; RhoGAP-p50rhoGAP; 1.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR049592; ARHGAP1_RhoGAP.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR PANTHER; PTHR45808:SF4; RHO GTPASE-ACTIVATING PROTEIN 8; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054081}.
FT DOMAIN 37..192
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 219..405
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW73283.1"
FT NON_TER 416
FT /evidence="ECO:0000313|EMBL:KFW73283.1"
SQ SEQUENCE 416 AA; 48228 MW; 1A77C27CEDADA79A CRC64;
LAPLELQKDE AEDTQSTQEE TFMSSPLEDP ELNINHPYYD VARHGIIQLA GDDNSGRKVI
TFSCCRMPPS HQLNHTRLLE YLKYTLDQYV ENDYTIVYFH YGLKSLNKPS LKWLQTAYKE
FDRKYKKNLK ALYVVHPTNF IKILWNIFKP LISHKFGKKI TYLNYLSDLR EHLKYDQLNI
PQEVIRHDEN LRGKQKGKLP LVVKVPPPRP PLPTQQFGVS LQYIKDKNKG ELIPPVMKET
VSYLKRKGLQ VEGLFRRSAS IQTIKDVQKL YNQGKSVNFD DYHDIHLPAV ILKTFLRELP
QPLLTFECYD HILGITSVES SLRVTRCKQI IQGLPEHNYV VLKYLICFLH MVSRESIYNR
MTASSLACVF GLNLIWPSKG TASLSALVPL NLFTELLIDF YTNIFNSRTV PGEILP
//
