ID A0A093P8Y5_PYGAD Unreviewed; 663 AA.
AC A0A093P8Y5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Dynamin-1-like protein {ECO:0000256|ARBA:ARBA00018833};
DE EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
DE Flags: Fragment;
GN ORFNames=AS28_09117 {ECO:0000313|EMBL:KFW73408.1};
OS Pygoscelis adeliae (Adelie penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae; Pygoscelis.
OX NCBI_TaxID=9238 {ECO:0000313|EMBL:KFW73408.1, ECO:0000313|Proteomes:UP000054081};
RN [1] {ECO:0000313|EMBL:KFW73408.1, ECO:0000313|Proteomes:UP000054081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS28 {ECO:0000313|EMBL:KFW73408.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.5;
CC Evidence={ECO:0000256|ARBA:ARBA00001837};
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Cytoplasmic vesicle, secretory
CC vesicle, synaptic vesicle membrane {ECO:0000256|ARBA:ARBA00004432}.
CC Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral
CC membrane protein {ECO:0000256|ARBA:ARBA00004184}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Mitochondrion outer membrane
CC {ECO:0000256|ARBA:ARBA00004450}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004450}. Peroxisome
CC {ECO:0000256|ARBA:ARBA00004275}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR EMBL; KL225530; KFW73408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093P8Y5; -.
DR STRING; 9238.A0A093P8Y5; -.
DR Proteomes; UP000054081; Unassembled WGS sequence.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF39; DYNAMIN-1-LIKE PROTEIN; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 3: Inferred from homology;
KW Biological rhythms {ECO:0000256|ARBA:ARBA00023108};
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW GTP-binding {ECO:0000256|RuleBase:RU003932};
KW Membrane {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003932};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000054081};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 1..269
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 571..662
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT REGION 489..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW73408.1"
FT NON_TER 663
FT /evidence="ECO:0000313|EMBL:KFW73408.1"
SQ SEQUENCE 663 AA; 74252 MW; 2B73F1B4B9E3ACEE CRC64;
QSSGKSSVLE SLVGRDLLPR GTGVVTRRPL ILQLVHVSPE DGRKTAGDEN EIDAEEWGKF
LHTKNKIYTD FDEIRQEIEN ETERISGNNK GISPEPIHLK IFSSNVVNLT LVDLPGMTKV
PVGDQPKDIE LQIRELILQF ISNPNSIILA VTAANTDMAT SEALKIAREV DPDGRRTLAV
ITKLDLMDAG TDAMDVLMGR VIPVKLGIIG VVNRSQLDIN NKKSVTDSIR DEYGFLQKKY
PSLANRNGTK YLARTLNRLL MHHIRDCLPE LKTRINVLAA QYQSLLNSYG EPVEDKSATL
LQLITKFATE YCNTIEGTAK YIETSELCGG ARICYIFHET FGRTLESVDP LGGLNTIDIL
TAIRNATGPR PALFVPEVSF ELLVKRQIKR LEEPSLRCVE LVHEEMQRII QHCSNYSTQE
LLRFPKLHDA IVEVVTCLLR RRLPVTNEMV HNLVAIELAY INTKHPDFAD ACGLMNNNIE
EQRRNRLARE LPSAVTRDKA APGGGDMSQE PGTGNWRGML KTSKAEEVSA EEKSKPPAAL
PASPQKGHAV NLLDVPVPVA RKLSAREQRD CEVIERLIKS YFLIVRKNIQ DSVPKAVMHF
LVNHVKDTLQ SELVGQLYKS LLLDDLLTES EDMAQRRKEA ADMLKALQRA SQIIAEIRET
HLW
//
