ID   A0A093P981_PYGAD        Unreviewed;       822 AA.
AC   A0A093P981;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Enhancer of filamentation 1 {ECO:0000313|EMBL:KFW68817.1};
DE   Flags: Fragment;
GN   ORFNames=AS28_04289 {ECO:0000313|EMBL:KFW68817.1};
OS   Pygoscelis adeliae (Adelie penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae; Pygoscelis.
OX   NCBI_TaxID=9238 {ECO:0000313|EMBL:KFW68817.1, ECO:0000313|Proteomes:UP000054081};
RN   [1] {ECO:0000313|EMBL:KFW68817.1, ECO:0000313|Proteomes:UP000054081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS28 {ECO:0000313|EMBL:KFW68817.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC       {ECO:0000256|ARBA:ARBA00004246}.
CC   -!- SIMILARITY: Belongs to the CAS family. {ECO:0000256|ARBA:ARBA00007848}.
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DR   EMBL; KL225213; KFW68817.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093P981; -.
DR   STRING; 9238.A0A093P981; -.
DR   Proteomes; UP000054081; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   CDD; cd11570; FAT-like_NEDD9_C; 1.
DR   CDD; cd11550; Serine_rich_NEDD9; 1.
DR   CDD; cd12002; SH3_NEDD9; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 1.
DR   Gene3D; 1.20.120.830; Serine-rich domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR021901; CAS_C.
DR   InterPro; IPR037362; CAS_fam.
DR   InterPro; IPR035746; NEDD9_SH3.
DR   InterPro; IPR014928; Serine_rich_dom.
DR   InterPro; IPR038319; Serine_rich_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR10654; CAS SCAFFOLDING PROTEIN; 1.
DR   PANTHER; PTHR10654:SF20; ENHANCER OF FILAMENTATION 1; 1.
DR   Pfam; PF12026; CAS_C; 1.
DR   Pfam; PF08824; Serine_rich; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054081};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          1..62
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          360..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          432..493
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFW68817.1"
FT   NON_TER         822
FT                   /evidence="ECO:0000313|EMBL:KFW68817.1"
SQ   SEQUENCE   822 AA;  91910 MW;  A5678A54D539C623 CRC64;
     QNLMARALYD NVPECAEELA FRKGDILTVI EQNTEGLEGW WLCSLHGRQG IVPGNRVKLL
     IGPVVQDSPG QDMSNSGLMH QSFNQQKIYQ VPSSHASARD PVYQVPPSHL NQGIYQIPTG
     HGLVGQDIYQ VPPSMQRCID GPALTNKVIT PVRSGQGYVY EFPSKYQKDT YDIPPVRPLQ
     GIYDIPPTSV KGPALPVPMG EAKALGVYDI PPAKGVYATP PSACRNDTGP RENLQGFSSP
     VGHSVRPEGV YDIPPPITKA TEKELNKFSP ESLLLPDGVP QKQNVYDIPM NHQNHFLGQQ
     IAAQKDVYDT PRGIPFPGQQ TGLSESLIPE GREGVYDVPP PVLQDTKGLQ DVTDGINRLS
     FSSTGSTRSN MSTSSTTSKD SSFSASTAQD KRLILDPDTA IERLYRLQQM VETAVNNLMA
     FVTADWRSYA YMEKHINEIH TAVDKVEQLL LEYLQFAKGS AANASCLSEF SLLNKMRREV
     QRLEDSHQIL TQTSHDLNSY NWSLNVLAVN RLQNKCDDLD RFVMVARTVP DDAKQLTTTI
     SVNAEVLFKQ ALSSSRFKNI PENIMNTPDY VYDNPHMQHH GEKAQNHCSS LPPLLSKGQH
     PHNTTSDSSE KSWMDDYDYV HLQGKEEFER QQKELLEKEN IIKQSKMELE HHQINQFQRL
     EQEITKPVEN DISKWKPPQA LQTANSTAAS HDSQLLLFYS DQCETHFNSL LNAIDAFFSC
     VNASQPPRIF VAHSKFVILS AHKLVFIGDM LTRQVTTQDI CNKVMNSSNQ LCELLKSVVL
     ATKMAALHYP NTAALQKMVD RVTELSHHAQ LFKLSLVQMA SL
//