ID A0A093Q4X4_9PASS Unreviewed; 622 AA.
AC A0A093Q4X4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Axin-2 {ECO:0000313|EMBL:KFW79262.1};
DE Flags: Fragment;
GN ORFNames=N305_07970 {ECO:0000313|EMBL:KFW79262.1};
OS Manacus vitellinus (golden-collared manakin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW79262.1, ECO:0000313|Proteomes:UP000053258};
RN [1] {ECO:0000313|EMBL:KFW79262.1, ECO:0000313|Proteomes:UP000053258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW79262.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KL670490; KFW79262.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093Q4X4; -.
DR STRING; 328815.ENSMVIP00005017443; -.
DR Proteomes; UP000053258; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd08707; RGS_Axin; 1.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 2.40.240.130; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR043581; Axin-like.
DR InterPro; IPR014936; Axin_b-cat-bd.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46102; AXIN; 1.
DR PANTHER; PTHR46102:SF1; AXIN-2; 1.
DR Pfam; PF08833; Axin_b-cat_bind; 1.
DR Pfam; PF00778; DIX; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00021; DAX; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50841; DIX; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW ProRule:PRU00069}.
FT DOMAIN 1..120
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 540..622
FT /note="DIX"
FT /evidence="ECO:0000259|PROSITE:PS50841"
FT REGION 319..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW79262.1"
FT NON_TER 622
FT /evidence="ECO:0000313|EMBL:KFW79262.1"
SQ SEQUENCE 622 AA; 70021 MW; 234B2AAFE12997E4 CRC64;
SLHSLLGDQD GAYLFRTFLE REKCVDTLDF WFACNGFRQM DLKDTKTLRV AKAIYKRYIE
NNSIVSKQLK PATKTYIRDS IKKQQIDSIM FDQAQTEIQT VMEENAYQMF LTSDIYLEYV
RSGGENPAYM NSNGLGSLKV VCGYLPTLNE EEEWSCADFK NKILPSVVGL SSKTLRVTAN
VRATETIENG YRSFKRNDPV NPYHVNSGYV FAPATSANDS EISSDALTDD SMSMTDSSVD
GIPPYRIGSK KQLQREMHRS VKANGQVSLP HFPRTHRLPK EMTPVEPAAF AAELISRLEK
LKQEQETMDC LEERLQQIKE DEEKEGSELP ASLQSSREMV NPQHPQHPLS LLPSGSYEED
PQAILDEHLS RVLKTPRTGT LLKRPGRGVE SVAPPAGDGG LPGPAGVQLP GGEADRAQNV
WQWMLESERQ NKHKPHSTQS TKKAYSSDCA KGAPGRHHPW GTAMPPLTPP NTLAQLEEAC
RRLAEVSKPQ KQRCSTSNQQ RDRNHSAAIQ GGGTPFCNAS LMTEDHKEPK KLPVVHTSQS
SELVVTYFFC GEEIPYRRML KAQSLTLGHF KEQLSKKGNY RYYFKKASDE FDCGAVFEEI
WEDETILPMY EGRILGKVER ID
//
