ID   A0A093QDS4_9PASS        Unreviewed;       515 AA.
AC   A0A093QDS4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Neutrophil cytosol factor 2 {ECO:0000313|EMBL:KFW86701.1};
DE   Flags: Fragment;
GN   ORFNames=N305_10548 {ECO:0000313|EMBL:KFW86701.1};
OS   Manacus vitellinus (golden-collared manakin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX   NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW86701.1, ECO:0000313|Proteomes:UP000053258};
RN   [1] {ECO:0000313|EMBL:KFW86701.1, ECO:0000313|Proteomes:UP000053258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW86701.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NCF2/NOXA1 family.
CC       {ECO:0000256|ARBA:ARBA00008051}.
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DR   EMBL; KL672661; KFW86701.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093QDS4; -.
DR   STRING; 328815.ENSMVIP00005004623; -.
DR   Proteomes; UP000053258; Unassembled WGS sequence.
DR   GO; GO:0043020; C:NADPH oxidase complex; IEA:InterPro.
DR   GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IEA:InterPro.
DR   GO; GO:0006909; P:phagocytosis; IEA:InterPro.
DR   GO; GO:0045730; P:respiratory burst; IEA:InterPro.
DR   CDD; cd06406; PB1_P67; 1.
DR   CDD; cd12046; SH3_p67phox_C; 1.
DR   CDD; cd11871; SH3_p67phox_N; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 2.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR034889; NCF2_SH3.
DR   InterPro; IPR035546; p67phox_SH3_1.
DR   InterPro; IPR000270; PB1_dom.
DR   InterPro; IPR034885; PB1_P67.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR15175:SF3; NEUTROPHIL CYTOSOL FACTOR 2; 1.
DR   PANTHER; PTHR15175; NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2; 1.
DR   Pfam; PF00564; PB1; 1.
DR   Pfam; PF00018; SH3_1; 2.
DR   Pfam; PF13181; TPR_8; 1.
DR   PRINTS; PR00499; P67PHOX.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00666; PB1; 1.
DR   SMART; SM00326; SH3; 2.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR   SUPFAM; SSF50044; SH3-domain; 2.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50002; SH3; 2.
DR   PROSITE; PS50005; TPR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          71..104
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DOMAIN          240..299
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          459..515
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          308..357
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          440..459
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..455
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         515
FT                   /evidence="ECO:0000313|EMBL:KFW86701.1"
SQ   SEQUENCE   515 AA;  57685 MW;  9774EC017F51E8D8 CRC64;
     MSLVETIRLW QEGVCAADRK EWSAALDAFT AVQNPPAKIC FNIGCIHLVL GRLAEAEEAF
     TRSIGCDKHL AVAYFQRGTV FYRRQNNEKA IEDFKEALAQ LRGNQLIDYK ILGLRYRLFA
     CEILCNIALV FATVENWGKA EEHLTLAMSM KSEPQHNKID RAMEAILKQK LCELVAIPVG
     KLFRPNEKQV AQLEKKDYLG KAMVVASVVD KDDFSGFAPL QPQTSGPPPR PKTPEILRAL
     QGQPHRVMYE FIPETAEELQ VLPGNIVFVL KKEKDNWATV MFNGKKGIVP CNFLEPVELQ
     NKLYIQEETP VEDEMPESPT STVPEKPRRP VPGQSGGAEG MGDPSSRFEE AEPPTSSPCV
     LKVHYKYTVA LRAEPGLSYT ELLDLVCKKL ELQPKHTELR YKPAESKELV TLTAKNLDAA
     WSQSKGNCLT VWCDLTEGEG FLPDSKPEES PQEATPEEMR PTQVVAQYNY EATQPEDLEF
     QAGDVILVLS KVNEDWLEGQ CNGKTGIFPS AFVQQ
//