ID A0A093QGC4_9PASS Unreviewed; 1974 AA.
AC A0A093QGC4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
DE Flags: Fragment;
GN ORFNames=N305_02726 {ECO:0000313|EMBL:KFW83122.1};
OS Manacus vitellinus (golden-collared manakin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW83122.1, ECO:0000313|Proteomes:UP000053258};
RN [1] {ECO:0000313|EMBL:KFW83122.1, ECO:0000313|Proteomes:UP000053258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW83122.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620; EC=3.1.3.48;
CC Evidence={ECO:0000256|ARBA:ARBA00001490};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family.
CC Receptor class 3 subfamily. {ECO:0000256|ARBA:ARBA00025789}.
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DR EMBL; KL671656; KFW83122.1; -; Genomic_DNA.
DR STRING; 328815.ENSMVIP00005005790; -.
DR Proteomes; UP000053258; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd00063; FN3; 9.
DR CDD; cd14617; R-PTPc-B; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 14.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR041201; PTPRJ_TM.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR46957; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR46957:SF3; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR Pfam; PF00041; fn3; 13.
DR Pfam; PF18861; PTP_tm; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00060; FN3; 17.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 16.
DR PROSITE; PS50853; FN3; 8.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Receptor {ECO:0000313|EMBL:KFW83122.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}.
FT DOMAIN 96..189
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 353..445
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 446..532
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 619..706
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 707..797
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 886..978
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1240..1333
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1334..1425
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1680..1940
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 1858..1931
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW83122.1"
FT NON_TER 1974
FT /evidence="ECO:0000313|EMBL:KFW83122.1"
SQ SEQUENCE 1974 AA; 220869 MW; C6F3CD9B64C91375 CRC64;
QAALGQAGCS ANLTERRVFG QSVRLRWGAA GRACNFSLSG RSEDGEATGC QPAHAGNGTY
DCTLRGLEAG TWYHLHIEPL SGGGALNISV QTDPLPPSRL EINKEKTTLT SLEVQWDPSS
GKVDFYNLVL FDDDNKKIQE VSVPGSISKT ENTFFNLIPG NKYNIVLSAV AGNKTTPELH
ISGYTVPSPV KNIQVSVKTD PIHASWSPGF GHVNCCRLML LDNHVPVHEI HQEDSPTSYT
FSGLTAGHLY NLSIITQAVG WESSTPAEVL DLTVTNDDSL DALKVKWRKP LGNFDFYNIT
LSHLGSVKGV KIVQPPITET HFDKLTPGRL YQVTARTISG ELFTDGMATG RTFPQNVSEL
QAGSGGWLRS LRVTWLPPAG DWERYHLLLW NRTALLLNTT LEKNTTEYLI CDVGLIPGRE
YGVDVVVESG DLQSKTSCTG RTAPEPVLQL RVKHANESSL SVMWMTPVAE WDSYVVSLGD
SDLTIIKKEL EKEAKEFTFT GLVPGRKYTA TITTISGTLS NWTSVEGRTV PAQVTDLIVA
SQGSTNSLFT NWTRAPGDVD SYQVLLIHEN VVIKNDTVPS ETNRYHFYAL KPGGLYSVVV
TTVSGGISSR QKIAEGSTVP SSVTGVTVNN SGRSDYLSVS WLPASGDVDS YLVTLSHHDQ
IVQTLTIPKS FSECSFSSLT PGTLYKVMIT TKSGKYENYT FSQERTVPSS VQGLTVSNSA
RSDYLKVSWL HASGYFDNYE VIIRNNNDFI QTKSVPKDEN ECVFTNLVPG RQYSVTVSTR
SGKYETSERV YGRTMPESVK ELTLSNRTTE DLQVTWSKAE GDVDKYEIQL LFNDMKIFPP
IFLGNTIEEY WFTALTPGRL YKILVLTISG DAQRATFIEG LTIPSVVRNI HVSPNGMTNS
LKVSWTPGGG DVDSYTVTIF QQNHQLDSQS VSKHVSEHTF HKLEAGEQYR VVVQSNSGTL
HNSLAAFGRT IPASVQELLA DHAYSSHSLL VTWQKAPGVA ERYDILLLNE QGVLLSNKSE
PAAAKQHKFE DLLAGKKYKI QVLTVSGGLF SKRAETVGRT VPAAVTNLKV TENTTDRLSF
SWTTSQGELD SYDIFLYNPD KSLHDRISGE QHLQQCSFQN LRQGRMYRMV IVTHSGDLTN
ESSIFGRTVP APVVGLKASN RNMTDSLWFT WGPAAGDVDF YELNLYNPNG TQKETWQRKD
LKEWHFQGLT PGRKYTLVVV THSGDLINTA NAEGRTAPSP PNTVSFTDVA NTSLSVTWLG
PPDWTDYDDF ELQWLPKDPL TVFNPYSSSK SKVRIIYGLR PGRLYEFSVR TVSGDNWKTY
SQSQSASVRT KPDKIQSLHC RPQTSTAIAC SWTPPDSDFD GYSIECKKMD TREVEFSKRI
EKDKSLLNIM TLVPHRRYLV SIKVHSADMT SEVVEDSTIT MIDRPPQPPP DIRVNKREVL
ITKSSINFTF NCSWFSDTNG AVKYFTVVVR EADGSEGPKP DEQHPLPSYL EYKHNDSIRI
YQTNYFASRC AENPDSDYKT FDIKLGGEME NLGGKCDPDH HKFCDGPLKP QTAYRISIRA
FTQLFSEDPK ELPKPLFADT FFSLPITTEA EPLFGVIEGV SAGLFLIVML VAVTALFVCR
QKVGSGHERS TARLSIRRER SLSVHLNLGQ KGNRKTSSPI KVSHFEAHFT KLQADSNYLL
SKEYEDLKDV GRNQTCDIAL LPENRGKNRY NNILPYDASR VKLSNVDDDP CSDYINASYI
PGNNFRREYI ATQGPLPGTK DEFWKMAWEQ NVHNIVMVTQ CVEKGRVKCD HYWPLDQDSL
YYGDLIVEML SESVLPEWTI REFKICSEEQ LDSTRLIRHF HYTVWPDHGV PETTQSLIQF
VRTVRDYINR TPDTGPAIVH CSAGVGRTGT FIALDRILQQ LDSKDTVDIY AAVHDLRLHR
VHMVQTECQY VYLHQCVRDV LRARKLRSEQ ENPLFPIYEN VNPEYPRDAV YSRH
//
