ID A0A093REX0_PHACA Unreviewed; 227 AA.
AC A0A093REX0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Prohibitin {ECO:0000256|RuleBase:RU366048};
DE Flags: Fragment;
GN ORFNames=N336_07212 {ECO:0000313|EMBL:KFW94562.1};
OS Phalacrocorax carbo (Great cormorant) (Pelecanus carbo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Suliformes; Phalacrocoracidae;
OC Phalacrocorax.
OX NCBI_TaxID=9209 {ECO:0000313|EMBL:KFW94562.1, ECO:0000313|Proteomes:UP000053238};
RN [1] {ECO:0000313|EMBL:KFW94562.1, ECO:0000313|Proteomes:UP000053238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N336 {ECO:0000313|EMBL:KFW94562.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Protein with pleiotropic attributes mediated in a cell-
CC compartment- and tissue-specific manner, which include the plasma
CC membrane-associated cell signaling functions, mitochondrial chaperone,
CC and transcriptional co-regulator of transcription factors and sex
CC steroid hormones in the nucleus. {ECO:0000256|ARBA:ARBA00037479}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004273, ECO:0000256|RuleBase:RU366048}.
CC -!- SIMILARITY: Belongs to the prohibitin family.
CC {ECO:0000256|ARBA:ARBA00009658, ECO:0000256|RuleBase:RU366048}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL442498; KFW94562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093REX0; -.
DR Proteomes; UP000053238; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03401; SPFH_prohibitin; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR000163; Prohibitin.
DR PANTHER; PTHR23222; PROHIBITIN; 1.
DR PANTHER; PTHR23222:SF1; PROHIBITIN-2; 1.
DR Pfam; PF01145; Band_7; 1.
DR PRINTS; PR00679; PROHIBITIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00022792, ECO:0000256|RuleBase:RU366048};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW ECO:0000256|RuleBase:RU366048};
KW Reference proteome {ECO:0000313|Proteomes:UP000053238}.
FT DOMAIN 1..131
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW94562.1"
FT NON_TER 227
FT /evidence="ECO:0000313|EMBL:KFW94562.1"
SQ SEQUENCE 227 AA; 25863 MW; 4898F410504EED94 CRC64;
RIPWFQYPII YDIRARPRKI SSPTGSKDLQ MVNISLRVLT RPNAAELPSM YQRLGLDYEE
RVLPSIVNEV LKSVVAKFNA SQLITQRAQV SLLIRRELTE RAKDFSLILD DVAITELSFS
REYTAAVEAK QVAQQEAQRA QFLVEKAKQE QKQKIVQAEG EATAAKMISC LGKFCVMWLV
SLTVLRICHS GLTLRRLLSD DSFNSQNRVY LTADNLVLNL QDEGFTR
//
