ID A0A093RYZ0_9PASS Unreviewed; 988 AA.
AC A0A093RYZ0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Anion exchange protein {ECO:0000256|RuleBase:RU362035};
DE Flags: Fragment;
GN ORFNames=N305_04850 {ECO:0000313|EMBL:KFW75954.1};
OS Manacus vitellinus (golden-collared manakin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW75954.1, ECO:0000313|Proteomes:UP000053258};
RN [1] {ECO:0000313|EMBL:KFW75954.1, ECO:0000313|Proteomes:UP000053258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW75954.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004554}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362035}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362035}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993, ECO:0000256|RuleBase:RU362035}.
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DR EMBL; KL669380; KFW75954.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093RYZ0; -.
DR STRING; 328815.ENSMVIP00005024444; -.
DR Proteomes; UP000053258; Unassembled WGS sequence.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR013769; Band3_cytoplasmic_dom.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR003024; Na/HCO3_transpt.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR NCBIfam; TIGR00834; ae; 1.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF105; SODIUM BICARBONATE COTRANSPORTER 3; 1.
DR Pfam; PF07565; Band_3_cyto; 2.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR PRINTS; PR01232; NAHCO3TRSPRT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU362035};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362035};
KW Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362035};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362035};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362035}.
FT TRANSMEM 433..455
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 462..481
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 520..543
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 550..568
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 648..666
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 686..704
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 734..753
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 774..798
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 834..853
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 860..879
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 911..942
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT DOMAIN 101..148
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 217..356
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 404..912
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..33
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW75954.1"
FT NON_TER 988
FT /evidence="ECO:0000313|EMBL:KFW75954.1"
SQ SEQUENCE 988 AA; 110723 MW; 71E389D46B62B9F8 CRC64;
GHRAVYIGVH VPLGKPGRRR HRHRGHRHHR RKKEKETDRE DGRESPSYDT PSQRVQFILG
TEDDDEHIPH DLFTEMDELY FRDGEEYEWR ETARWLKFEE DVEDGGDRWS KPYVATLSLH
SLFELRSCIL NGTVMLDMRA NTLDEIAVLL SYLLPSSRAG TPAASRCTTP VTTPQNTPPS
SPTCSLLPTT SAQPSPLQGK ELLVSPATPG NLDTGKSGDV KGTGTGGSRE NSTVDFSKVD
MNFMRKIPSG AEASNVLVGE VDFLERPIIA FVRLSPAVLL SGLTEVPVPT RFLFLLLGPV
GKAPQYHEIG RSIATLMTDD VFHDVAYKAK DRNDLLSGID EFLDQVTVLP PGEWDPSIRI
EPPKSVPSQE KRKAPKFPNG STPTGETLKE EGHHAGPELQ RTGRLFGGLI LDIQRKAPFF
LSDFKDALSL QCLASILFLY CACMSPVITF GGLLGEATQG RISAIESLFG ASLTGIAYSL
FAGQPLTILG STGPVLVFEK ILFKFCRDYD LSYLSLRTSI GLWTAFLCIV LVATDASSLV
CYITRFTEEA FAALICIIFI YEALEKLFHL GEVYAFNMHN DLNKLTLYSC VCSEPEKPSN
ETLRVWRSMN KSGEDIAWSN LTVSECLKFH GVFRGSACGH HGPYIPDVLF WSVILFFTTF
FLSSFLKKFK TKRYFPTKVR STISDFAVFL TIVIMVLIDY FIGIPSPKLH VPEKFEPTRK
DRGWFIDPLG SNPWWTLLVA AVPALLCTIL IFMDQQITAV IINRKEHKLK KGCGYHLDLL
MVGVMLGICS LMGLPWFVAA TVLSISHVNS LKVESQCSAP GEQPKFLGIR EQRVTGLMIF
VLMGMSVFMT SVLKFIPMPV LYGVFLYMGV SSLKGIQFFD RIKLFGMPAK HQPDLIYLRY
VPLWKVHIFT VIQLTCLVLL WVIKASAAAV VFPMMVLALV FIRKLMDLCF TKRELSWLDD
LMPESKKKKE DDKKIKEKEV SVKTIKLS
//
