ID A0A093S0U1_9PASS Unreviewed; 182 AA.
AC A0A093S0U1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Interferon alpha-2 {ECO:0000313|EMBL:KFW76584.1};
DE Flags: Fragment;
GN ORFNames=N305_03725 {ECO:0000313|EMBL:KFW76584.1};
OS Manacus vitellinus (golden-collared manakin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW76584.1, ECO:0000313|Proteomes:UP000053258};
RN [1] {ECO:0000313|EMBL:KFW76584.1, ECO:0000313|Proteomes:UP000053258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW76584.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Has antiviral activities. {ECO:0000256|ARBA:ARBA00002718}.
CC -!- SIMILARITY: Belongs to the alpha/beta interferon family.
CC {ECO:0000256|ARBA:ARBA00011033, ECO:0000256|RuleBase:RU000436}.
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DR EMBL; KL669492; KFW76584.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093S0U1; -.
DR STRING; 328815.ENSMVIP00005010769; -.
DR Proteomes; UP000053258; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.10; -; 1.
DR InterPro; IPR009079; 4_helix_cytokine-like_core.
DR InterPro; IPR000471; Interferon_alpha/beta/delta.
DR PANTHER; PTHR11691:SF37; INTERFERON OMEGA-1; 1.
DR PANTHER; PTHR11691; TYPE I INTERFERON; 1.
DR Pfam; PF00143; Interferon; 1.
DR PRINTS; PR00266; INTERFERONAB.
DR SMART; SM00076; IFabd; 1.
DR SUPFAM; SSF47266; 4-helical cytokines; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW ECO:0000256|RuleBase:RU000436}; Cytokine {ECO:0000256|RuleBase:RU000436};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..182
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001886938"
FT NON_TER 182
FT /evidence="ECO:0000313|EMBL:KFW76584.1"
SQ SEQUENCE 182 AA; 21748 MW; B4C9728D89507462 CRC64;
MNAFGLIQIG LILLCTTIIC NHQCNHLLLQ QRKMIENSLQ LLDKMGKNFP QRCLREKMSF
RFPKQVLQPR QKETVRIAIE EIFQHIFYIF SKNLTLAAWD GTALDQFQNG LYQQIEQLEA
CVIKKHTHYC WSKEVSRLKL KKYFQKIDCF LKDKQHNLCS WEISRAEMRR CLQLIDKVTR
KL
//
