ID   A0A093SC63_9PASS        Unreviewed;       477 AA.
AC   A0A093SC63;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 28.
DE   SubName: Full=MARVEL domain-containing protein 2 {ECO:0000313|EMBL:KFW80409.1};
DE   Flags: Fragment;
GN   ORFNames=N305_10128 {ECO:0000313|EMBL:KFW80409.1};
OS   Manacus vitellinus (golden-collared manakin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX   NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW80409.1, ECO:0000313|Proteomes:UP000053258};
RN   [1] {ECO:0000313|EMBL:KFW80409.1, ECO:0000313|Proteomes:UP000053258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW80409.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ELL/occludin family.
CC       {ECO:0000256|ARBA:ARBA00009171, ECO:0000256|PROSITE-ProRule:PRU01324}.
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DR   EMBL; KL670897; KFW80409.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093SC63; -.
DR   STRING; 328815.ENSMVIP00005008014; -.
DR   Proteomes; UP000053258; Unassembled WGS sequence.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 6.10.140.340; -; 1.
DR   InterPro; IPR031176; ELL/occludin.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR010844; Occludin_ELL.
DR   PANTHER; PTHR23288:SF3; MARVEL DOMAIN-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR23288; OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   Pfam; PF07303; Occludin_ELL; 1.
DR   SUPFAM; SSF144292; occludin/ELL-like; 1.
DR   PROSITE; PS51225; MARVEL; 1.
DR   PROSITE; PS51980; OCEL; 1.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW   ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        115..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        210..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        262..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          111..286
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
FT   DOMAIN          362..473
FT                   /note="OCEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51980"
FT   REGION          31..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFW80409.1"
FT   NON_TER         477
FT                   /evidence="ECO:0000313|EMBL:KFW80409.1"
SQ   SEQUENCE   477 AA;  54585 MW;  064D654D9FC04C03 CRC64;
     IPDSWKNFFK GRRHPGSSWD STASDIRYIS DGVECSPPAT PAPPQPGAKT VPSSYRDPYG
     GSGGSYNSGK EAEAMLPSDD PLGSLERRAG TGRTYSERVE EYHQRYAYMK SWAGLLRILG
     VAELLLGAAV FACVTAYVHK DNEWYNMFGY SQPYGYGAGS AYSGYSYSGP KTPFVLVAAG
     MAWIVTMVLL VLGMSMYYRT ILLDSNWWPL TEFGINVALF FLYMSAAIVY VNDTNRGGLC
     YYQLFKTPIN ASFCRVEGGQ TAAIIFLFVT VIIYLISAVV SLKLWRHEGA RRRRELMEQE
     VRSTCDVLPC RRWSRIRCLL CSSDDRPREE VSYRQLKSVE RKPELLNGHI PAGHIPKPIV
     MPDYLAKYPV IQTNEMRDRY KAVFNDQFAE YKELSVEVHA VLKKFDELDA LLKQLPHHPE
     SIYEQERISK VLQEYKKKKN DPAFLEKKER CEYLKNKLSH IKQRIQDYDK VMNWNVE
//