ID A0A093SEL1_9PASS Unreviewed; 821 AA.
AC A0A093SEL1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Lysine-specific histone demethylase 1B {ECO:0000313|EMBL:KFW81169.1};
GN ORFNames=N305_06007 {ECO:0000313|EMBL:KFW81169.1};
OS Manacus vitellinus (golden-collared manakin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW81169.1, ECO:0000313|Proteomes:UP000053258};
RN [1] {ECO:0000313|EMBL:KFW81169.1, ECO:0000313|Proteomes:UP000053258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW81169.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL671098; KFW81169.1; -; Genomic_DNA.
DR RefSeq; XP_008922414.1; XM_008924166.2.
DR AlphaFoldDB; A0A093SEL1; -.
DR STRING; 328815.ENSMVIP00005019331; -.
DR GeneID; 103757969; -.
DR CTD; 221656; -.
DR OrthoDB; 5402444at2759; -.
DR Proteomes; UP000053258; Unassembled WGS sequence.
DR GO; GO:0140682; F:FAD-dependent H3K4me/H3K4me3 demethylase activity; IEA:UniProt.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.100; -; 1.
DR Gene3D; 3.90.660.10; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR007526; SWIRM.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR PANTHER; PTHR10742:SF413; LYSINE-SPECIFIC HISTONE DEMETHYLASE 1B; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR Pfam; PF04433; SWIRM; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50934; SWIRM; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:KFW81169.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW Transferase {ECO:0000313|EMBL:KFW81169.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 134..194
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 274..372
FT /note="SWIRM"
FT /evidence="ECO:0000259|PROSITE:PS50934"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 821 AA; 92327 MW; 901410B57EB3DE51 CRC64;
MSTGRVRTKK KACSSDQSPD SLPVRSSGRQ VKKKAAEAAA DDDDEASEKK YRKCEKAGCT
ATCPVCFASA AERCAKNGYT SRWYHLSCGE HFCNECFDHY YRSHKDGYEK YTAWKRIWTS
NGKSEPSPKA FMADQQLPYW VQCTKPDCGK WRQLTKEIQL TPQIAKTYRC GMKLNNSTKT
EGSDQCSMPE DLRVAEVSDH WWYSMLILPP LLKDSVAAPF LAAYYPDCVG MSPSCTSTNR
LPGESNLVKL EHLKSVPNLT VAGMNKYFQP FYQPNECGKA LCVRPDVMEL DELYEFPEYS
RDPTMYLALR NLILALWYTN CKEALTPQKC IHHIIVRGLV RIRCVQEMER ILYFMTRKGL
INTGLLSVGP DQYLLPKEYH SKSVIIVGAG AAGLAAARQL HNFGIKVIIL EAKDRIGGRV
WDDKTFTGVT VGRGAQIVNG CVNNPVALMC EQLGIKMHKL GEKCDLIQEG GRITDPTIDK
RMDFHFNAIL DVVSEWRKDK TQHQDVPLGE KIQEIYKAFI QESGIQFSEL EEKVLQFHLS
NLEYACGSNL SQVSARSWDH NEFFAQFAGD HTLLTVGYST VIEKLAEGLD IRLNFPVQSI
DYSGEEVHVT TADGTVWTTQ KVLVTVPLAL LQKNAIQFNP PLSEKKIKAI NSLGAGVIEK
IALQFPYRFW DSKIQGADFF GHVPPNSSQR GLFSVFYDMD PEGKESILMS VVTGDAVVTI
KNLDDQQVLQ QCMTVLRELF KEQEVPDPVK FFVTRWSNDP WLQMAYSFVK TGGSGEAYDI
IAEDIQGKIF FAGEATNRHF PQTVTGAYLS GVREASKIAA F
//
