ID A0A093SUJ7_PHACA Unreviewed; 696 AA.
AC A0A093SUJ7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Protein-glutamine gamma-glutamyltransferase 6 {ECO:0000313|EMBL:KFW86179.1};
DE Flags: Fragment;
GN ORFNames=N336_04681 {ECO:0000313|EMBL:KFW86179.1};
OS Phalacrocorax carbo (Great cormorant) (Pelecanus carbo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Suliformes; Phalacrocoracidae;
OC Phalacrocorax.
OX NCBI_TaxID=9209 {ECO:0000313|EMBL:KFW86179.1, ECO:0000313|Proteomes:UP000053238};
RN [1] {ECO:0000313|EMBL:KFW86179.1, ECO:0000313|Proteomes:UP000053238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N336 {ECO:0000313|EMBL:KFW86179.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|PIRSR:PIRSR000459-2};
CC Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR000459-2};
CC -!- SIMILARITY: Belongs to the transglutaminase superfamily.
CC Transglutaminase family. {ECO:0000256|ARBA:ARBA00005968}.
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DR EMBL; KL418309; KFW86179.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093SUJ7; -.
DR Proteomes; UP000053238; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR InterPro; IPR023608; Transglutaminase_animal.
DR InterPro; IPR013808; Transglutaminase_AS.
DR InterPro; IPR008958; Transglutaminase_C.
DR InterPro; IPR036238; Transglutaminase_C_sf.
DR InterPro; IPR001102; Transglutaminase_N.
DR PANTHER; PTHR11590; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR PANTHER; PTHR11590:SF50; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 6; 1.
DR Pfam; PF00927; Transglut_C; 2.
DR Pfam; PF01841; Transglut_core; 1.
DR Pfam; PF00868; Transglut_N; 1.
DR PIRSF; PIRSF000459; TGM_EBP42; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49309; Transglutaminase, two C-terminal domains; 2.
DR PROSITE; PS00547; TRANSGLUTAMINASES; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|PIRSR:PIRSR000459-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR000459-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000053238};
KW Transferase {ECO:0000313|EMBL:KFW86179.1}.
FT DOMAIN 266..358
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT REGION 464..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 274
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 332
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 355
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT BINDING 395
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 397
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 444
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 449
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW86179.1"
FT NON_TER 696
FT /evidence="ECO:0000313|EMBL:KFW86179.1"
SQ SEQUENCE 696 AA; 78503 MW; 691D316D0887EC92 CRC64;
FTDLTPTHIS WQPSVNAGAH HTDRYANTEL TVRRGQAFTI TLYFNRPRQT GEKLAFVTEI
GPAPSESHRT KAVFNLSEVG ASGWTAAQAP SESGYMNFTI SSPADAVIGR YNLTLQVTSG
NKIFSRYLGQ FVLLFNPWCP GDNVYMADEN ERQEYVLNEN GIIFVGNAKY IEARGWYYGQ
FQDDLLNICL TMLDLSLYYR QNSAIDVSRR GDPKYVGRVI SSMINGNDND NGVLLGKWQG
SFHSHENPSR WDGSVVILQK WRQDNYKPVQ YGQCWVFAGV MCTVLRCLGI PTRLVSNFNS
AHDVDRNLSI DKYYDSSGKS LNISKDSTWD YHVWNESWFI RPDLGTSYNG WQVLDATPQE
QSKGLFQCGP ASVIAIKEGD IHLDYDTLFV YTEVNADCNR WIVYNDGTKK RVYCDTEIIG
RFISTKAVGS NSRVDITCNY KYPEGSSEER RVYKKALAKL FGSNTTEGHT ESPHERPSET
IRNPGISGKF KLAEPPVFGK DITLILSLNN LSSDHKTVKV DFSASTVLYT RRAVTEVLKA
TTSVDLGSKK GKHIRLKIPY SSYGKYLTTD KRIQVTALCE VMHMHGVKLL VEKTIILEDT
NIIIKIPRRV VVNKAVTLEI SYANPLPEPV NHCVLLVTLM NQQVKIHLAR LGPRERSKIY
FEFTPRKSGP LQLQVDFSCD KFSHVKGFVT IAVARA
//
