ID   A0A093V5Y1_TALMA        Unreviewed;      1598 AA.
AC   A0A093V5Y1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=DNA damage-binding protein 1 {ECO:0000256|ARBA:ARBA00014577};
GN   ORFNames=GQ26_0480120 {ECO:0000313|EMBL:KFX42136.1};
OS   Talaromyces marneffei PM1.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=1077442 {ECO:0000313|EMBL:KFX42136.1, ECO:0000313|Proteomes:UP000029285};
RN   [1] {ECO:0000313|Proteomes:UP000029285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PM1 {ECO:0000313|Proteomes:UP000029285};
RX   PubMed=25330172; DOI=10.1371/journal.pgen.1004662;
RA   Yang E., Wang G., Cai J., Woo P.C., Lau S.K., Yuen K.-Y., Chow W.-N.,
RA   Lin X.;
RT   "Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms
RT   of Dimorphic Transition in Penicillium marneffei.";
RL   PLoS Genet. 10:e1004662-e1004662(2014).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFX42136.1}.
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DR   EMBL; JPOX01000048; KFX42136.1; -; Genomic_DNA.
DR   Proteomes; UP000029285; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR10644:SF21; CLEAVAGE_POLYADENYLATION SPECIFICITY FACTOR A SUBUNIT N-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   4: Predicted;
FT   DOMAIN          432..937
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10433"
FT   DOMAIN          1251..1529
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03178"
SQ   SEQUENCE   1598 AA;  178650 MW;  C33899B95D9B8672 CRC64;
     MDDIGGGDDT HETDDPLFGI FPDRRGDDYG DNNDTFCAVC GVPLNVLRLL EYRKTVLHLT
     QDDTILRTGH KSIRVPTNID LFGTVQWPWG SRYTAEYEAA PFPIEDLVSE ILYYLEPLPA
     ESSSISAPTL QSQMNRLLIE IQQQIYQYLH PFKNPPTECS RHLASSTWKD LLLHGKLLPW
     LWDLEEPEVT VIDRDILTGS IRDLSVNKQA VQADMGQSPS IELDEDLWDW ERLVRQLARY
     DSFELGGVLE CLPEALLNRR RIWRLLDEAR QDDTSIKQRC VEKRAVLGYI ISSGSVVETF
     SLYHTGILES VSNEVHYHQM SDIMSLTKPK IGLLSQTIVP SPSIQFALPA RLRNKRHNDV
     VFVYERSLVI REIISDTYLE DVMVNSDFDA NIVAAKTVKI DQDTLEGAEI KLNAQKSPLE
     VDRQDDSLPG HILALTLDSR ELLFLYCHSG SPDNDVGFVH FRRALPSDVS ISERFGRHLA
     VDPRSRAVAV AAPADFFGVF MLKASGELHS QIKGGTLAPI AEERFYRLEG HIMFMDFLYS
     PENEKNNIVL LLIVSRGPLT YAMHYIWDSE KGVRQAQPKP ITSKLPDFCR LPNLLIPLTK
     SSNYLLITPS FIIINRNPLS PNSKRVKQRC SDLISKSPSI WAKWARPYRH PKYDILHDDV
     FLCREDGRLT YVEIDNKGQI ESINVIGQLD CEVDAAFDTI DFNHPSHGGD LLIAAGSTGH
     GGLFIQTARQ NPECVQRFVN WAPVFDTVIV PPLQKKAGHE FDMTKDLSDD LHLYVSSASS
     NNSGAVYEFR HGYEAQIGMI IPLEDFTTAR AVWVIPDFSQ DGTYFLISDP ISSALMHLSR
     NESGEGDEIY AVDGSDLSLD LSVNSLAAGY TSTGVLFQVT SNAVRAVLLN NPEINCVSDF
     SIDQTVLVAT LSEELELVAV ALRSEQGISI QVGRAILNDC SLNIDFTGKT IHVEHEPISI
     VVEALKDGAY LFVGTSDGYL AYYRVEQDEL VCIGEYMLNL PNDHVSKAIE SIALIDGVGT
     EKAALYCGLR SGLLVSLEII FETMSINQRA AKRFGQTVVK LLRKENTVLV TCGMGFWRIS
     DISIGSASDF DLQRIWITDQ NDSTYTQKGI EGLTIVNASQ YPSTNSLGGS LVCISDEQLL
     VCSLDRRAKA VPRMVELPGT VNRIQYSAHL KCLVVAYITT ELETEAGTVP ENSIIRRYMR
     PHLSFLNFDD YNSHLLSYQH NLEPLDSSHA QKPVGSSGER ITCILDWIPE TGGQKYHLLV
     VGTARKTQEQ SGRVIFLNAK RNAANPEQID CSLKYIHTFD GPVRAIAAYG DSTIMVASGN
     DIIPIAPRLP NGGEQWAAAA RFKLTSPGVS IIVRDTLLYI STARESLVIL QVVNKKLELY
     AQDGVRHESL SHQYIGGEND LTLVSHRGGT ISAFSAAGVT DMDKIISPAI AEAQLPVSII
     RLNACDDPSL QSSSSPVVYG TTTDGTIYRI STLTEKQWRL LRFLQNLCSK DSTLSPFLSA
     RKRRWTWADI EPQAKKPSSM HVDGDILSRL LPKGTTYLRK MLRSDQEEEL DNAVMPPPKT
     YIELFVELFD DVFGEDIVEG DRLDYLMSWL RKLLQRRL
//