ID A0A093VF37_TALMA Unreviewed; 805 AA.
AC A0A093VF37;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Quinate repressor protein {ECO:0000313|EMBL:KFX45311.1};
GN ORFNames=GQ26_0241410 {ECO:0000313|EMBL:KFX45311.1};
OS Talaromyces marneffei PM1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=1077442 {ECO:0000313|EMBL:KFX45311.1, ECO:0000313|Proteomes:UP000029285};
RN [1] {ECO:0000313|EMBL:KFX45311.1, ECO:0000313|Proteomes:UP000029285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PM1 {ECO:0000313|EMBL:KFX45311.1,
RC ECO:0000313|Proteomes:UP000029285};
RX PubMed=25330172; DOI=10.1371/journal.pgen.1004662;
RA Yang E., Wang G., Cai J., Woo P.C., Lau S.K., Yuen K.-Y., Chow W.-N.,
RA Lin X.;
RT "Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms
RT of Dimorphic Transition in Penicillium marneffei.";
RL PLoS Genet. 10:e1004662-e1004662(2014).
CC -!- SIMILARITY: In the 2nd section; belongs to the type-I 3-dehydroquinase
CC family. {ECO:0000256|ARBA:ARBA00006477}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the shikimate kinase
CC family. {ECO:0000256|ARBA:ARBA00009349}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX45311.1}.
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DR EMBL; JPOX01000024; KFX45311.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093VF37; -.
DR eggNOG; KOG0692; Eukaryota.
DR HOGENOM; CLU_008871_0_1_1; -.
DR Proteomes; UP000029285; Unassembled WGS sequence.
DR GO; GO:0003855; F:3-dehydroquinate dehydratase activity; IEA:InterPro.
DR CDD; cd00502; DHQase_I; 1.
DR CDD; cd01065; NAD_bind_Shikimate_DH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR001381; DHquinase_I.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041121; SDH_C.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR006151; Shikm_DH/Glu-tRNA_Rdtase.
DR PANTHER; PTHR21090; AROM/DEHYDROQUINATE SYNTHASE; 1.
DR PANTHER; PTHR21090:SF17; QUINATE REPRESSOR PROTEIN; 1.
DR Pfam; PF01487; DHquinase_I; 1.
DR Pfam; PF18317; SDH_C; 1.
DR Pfam; PF01488; Shikimate_DH; 1.
DR Pfam; PF01202; SKI; 1.
DR PRINTS; PR01100; SHIKIMTKNASE.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
FT DOMAIN 612..655
FT /note="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA
FT reductase"
FT /evidence="ECO:0000259|Pfam:PF01488"
FT DOMAIN 751..781
FT /note="SDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18317"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 805 AA; 89489 MW; 6CEDDDC43E1B8544 CRC64;
MSPMVPAKKP PSKVHMLGTP ASKRNFAPDA SLVLVGIRGS GKRSLGFIAA AALNRRFITE
DYYFKEVTGL TRHEFLLKFG SHEFQRRDVE VLKMMLDNHR THCVIECGLG SLTRIIQEHL
RQYALTNPVV YLLRDMDQIQ RLLQLQDFSV KRLGNGDPYH RTCSNFEYYN LEEPVPVDLS
LEEGAPDRRS VNYSFKLKDA KEDFTQFVRF ITGATTTGPG LDSPFVLLET PPESRPHTHA
VLLRLSALHN NLVDLAKLES GGDAIELCID MWNPDAVSTV AKHVSVLRRI AKLPIIYSID
AGALGLDARI SDPAVKNGDL YFQILEYGLR LGVEYLAIHL DHDHTRLTQI VQSRGMTKII
GHFTIDISSG ISWEDEACLS IYIEAERLGC QLVRIVRLAT TREENDSVRK FVDRVKALSG
SHPPIIAFNI GPIGRSSQVF NNTLTSVAHP AISPSALRAS DPQITSQDAI RALVQSYMLD
PLKFYILGAS VAYSISPAMH NAAYASCGLS HVYRIPDAPS LALLDEWCHD PHFGGSSVSP
CRAIGAINTV MPLRTSADGN IYPLSEQASR RNEAGPIAAW WGENTDWISI MVCLRRNLSP
RNAISPIRTT GLVIGAGGMA RAAIYAMLQL GCRKIFILNR TLSRAEEVAR HFNSWVASSH
TESDAAVRVL RSADEPWPSE LAFPSMIVSC VPENRIQGQP PANFVMPLQW LGSPSGGVVV
ELAYNSLDTP LVRQLRRYRE ETDTPWVLID GLEIVAEQGF AQWELMTGRK APRRLMMTEV
LRNYMGENGR LDEKTIRARL DAFSG
//
