ID A0A093VJW8_TALMA Unreviewed; 663 AA.
AC A0A093VJW8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Peroxisomal targeting signal receptor {ECO:0000256|ARBA:ARBA00014710};
DE AltName: Full=Peroxin-5 {ECO:0000256|ARBA:ARBA00032505};
GN ORFNames=GQ26_0022440 {ECO:0000313|EMBL:KFX52852.1};
OS Talaromyces marneffei PM1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=1077442 {ECO:0000313|EMBL:KFX52852.1, ECO:0000313|Proteomes:UP000029285};
RN [1] {ECO:0000313|EMBL:KFX52852.1, ECO:0000313|Proteomes:UP000029285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PM1 {ECO:0000313|EMBL:KFX52852.1,
RC ECO:0000313|Proteomes:UP000029285};
RX PubMed=25330172; DOI=10.1371/journal.pgen.1004662;
RA Yang E., Wang G., Cai J., Woo P.C., Lau S.K., Yuen K.-Y., Chow W.-N.,
RA Lin X.;
RT "Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms
RT of Dimorphic Transition in Penicillium marneffei.";
RL PLoS Genet. 10:e1004662-e1004662(2014).
CC -!- SUBUNIT: Interacts (via WxxxF/Y and LVxEF motifs) with PEX14; promoting
CC translocation through the PEX13-PEX14 docking complex.
CC {ECO:0000256|ARBA:ARBA00038659}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Peroxisome matrix
CC {ECO:0000256|ARBA:ARBA00004253}.
CC -!- SIMILARITY: Belongs to the peroxisomal targeting signal receptor
CC family. {ECO:0000256|ARBA:ARBA00005348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX52852.1}.
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DR EMBL; JPOX01000002; KFX52852.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093VJW8; -.
DR eggNOG; KOG1125; Eukaryota.
DR HOGENOM; CLU_013516_3_0_1; -.
DR Proteomes; UP000029285; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005782; C:peroxisomal matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR024111; PEX5/PEX5L.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10130:SF0; GH08708P; 1.
DR PANTHER; PTHR10130; PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Receptor {ECO:0000313|EMBL:KFX52852.1};
KW Thioester bond {ECO:0000256|ARBA:ARBA00022966};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT REPEAT 371..404
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 524..557
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 73293 MW; 1EA21C45A2FDD3F2 CRC64;
MSFLGGSECS TAGNPLTQFT KHVQDDKSLQ RDRLVGRAPG MQESMRSRGM AGPGDQMMDE
FMQQSNHVQH HDPAHNFAME QLRRGIETLQ HTPQRTGSPG WAAEFDTGEQ ARMEAAFQGP
TAAPAALDSR GPGFSAAEFS RFQQQHRTAS PITQSTQSPM MSGYQRPMMG GYMGAMGGMG
AMGMMGPSYM PMQQQQQPGV QEQEGKGKGR MVELDDENWE AQFAEMDAAG QEAFDDQANH
AMEAELNDLD RSVHSTPLQN QSEGFEQFER VWQSAQAENA SATTSRQLAD DDFEEVANLH
LGDANGWEGF DSLNTRFRDP QLGDYLFEED NMFKAVGNPF EEGMKIMQEG GNLSLAALAF
EAAVQKDPQH VQAWTMLGSA QAQNEKENPA LRALEQALKL DPNNLDALMG LAVSYTNEGY
DSTAYRTLER WLSVKYPQVI SPNDLSADTD VGFTDRQLLH DKVTDLFIQA AQLSPSGEHM
DPDVQVGLGV LFYCAEEYGK AVDCFSAALA STESGTSNQQ GQVHLLWNRL GATLANSGRS
EEAIEAYEKA LTINPNFVRA RYNLGVSCIN IGCYPEAAQH LLGALAMHKV VEQQGREKAR
EIVEGVDGID DAELERMMHI TQNQSTNLYD TLRRVFTSMA RRDLADMVVS GMDVDVFRRE
FEF
//
