ID A0A093VK96_TALMA Unreviewed; 362 AA.
AC A0A093VK96;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Demethylsterigmatocystin 6-O-methyltransferase {ECO:0000313|EMBL:KFX50419.1};
GN ORFNames=GQ26_0071510 {ECO:0000313|EMBL:KFX50419.1};
OS Talaromyces marneffei PM1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=1077442 {ECO:0000313|EMBL:KFX50419.1, ECO:0000313|Proteomes:UP000029285};
RN [1] {ECO:0000313|EMBL:KFX50419.1, ECO:0000313|Proteomes:UP000029285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PM1 {ECO:0000313|EMBL:KFX50419.1,
RC ECO:0000313|Proteomes:UP000029285};
RX PubMed=25330172; DOI=10.1371/journal.pgen.1004662;
RA Yang E., Wang G., Cai J., Woo P.C., Lau S.K., Yuen K.-Y., Chow W.-N.,
RA Lin X.;
RT "Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms
RT of Dimorphic Transition in Penicillium marneffei.";
RL PLoS Genet. 10:e1004662-e1004662(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX50419.1}.
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DR EMBL; JPOX01000007; KFX50419.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093VK96; -.
DR eggNOG; KOG3178; Eukaryota.
DR HOGENOM; CLU_005533_5_0_1; -.
DR Proteomes; UP000029285; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF11; O-METHYLTRANSFERASE (AFU_ORTHOLOGUE AFUA_2G17820)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KFX50419.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:KFX50419.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 176..347
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT REGION 336..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 40075 MW; 5A99053305104CF1 CRC64;
MASLSNLSDT IASTLSNLPP QDQIQDTSNS SGTALPSATA FLFLGIGFLA LVAVRWTTNI
GRVKHYGIVI IRIAQGMGVF NAFVESQGAD LSLKELSSKV KGDEKLLKRV MRFLCSYKVF
TQAANGIYKP SPLAMMLGGL PGDMVKHCHN IMQISAKLFD YFEKNDYKNP EDAFDAPFQF
AFKTKQHYFD WLRENPAAQS AFNSVMTFSQ QLRGRNWFEI YPVAEKLNSS SDRTLLVDIG
GGVGHDVIEF KKQFSDMPGD LVVQDLPRVI ESIDGALPDG ITAIGHDMFE PQSIRGAKAY
YLRTVLHDWP DKQALEALAR IREAMVEDSI LLIHEHTTPD TPRGASRSSN AGHPNDGNIF
LP
//
