ID A0A093X222_9PEZI Unreviewed; 1989 AA.
AC A0A093X222;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=DEAD/DEAH box helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=V490_08995 {ECO:0000313|EMBL:KFX86633.1};
OS Pseudogymnoascus sp. VKM F-3557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX86633.1, ECO:0000313|Proteomes:UP000029320};
RN [1] {ECO:0000313|EMBL:KFX86633.1, ECO:0000313|Proteomes:UP000029320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX86633.1,
RC ECO:0000313|Proteomes:UP000029320};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the YIP1 family.
CC {ECO:0000256|ARBA:ARBA00010596}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX86633.1}.
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DR EMBL; JPJS01002604; KFX86633.1; -; Genomic_DNA.
DR STRING; 1437433.A0A093X222; -.
DR HOGENOM; CLU_000809_0_0_1; -.
DR Proteomes; UP000029320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR CDD; cd17923; DEXHc_Hrq1-like; 1.
DR CDD; cd18797; SF2_C_Hrq; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR014939; CDT1_Gemini-bd-like.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR018973; MZB.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR InterPro; IPR006977; Yip1_dom.
DR PANTHER; PTHR47957; ATP-DEPENDENT HELICASE HRQ1; 1.
DR PANTHER; PTHR47957:SF3; ATP-DEPENDENT HELICASE HRQ1; 1.
DR Pfam; PF08839; CDT1; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF09369; MZB; 1.
DR Pfam; PF00638; Ran_BP1; 1.
DR Pfam; PF04893; Yip1; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00160; RanBD; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50196; RANBD1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 171..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 679..786
FT /note="RanBD1"
FT /evidence="ECO:0000259|PROSITE:PS50196"
FT DOMAIN 1206..1389
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1429..1582
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 847..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1041..1060
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1957..1989
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..39
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..364
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..664
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..683
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..867
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1973..1989
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1989 AA; 217016 MW; 522024B193296341 CRC64;
MASSANPYQN YTQPQASDHD DDLIDPDTAS LDDLDDPLDD APNYSARAPL TGNIGSSSSS
RPLNESYLTS AMPGDDRRAP TNTIDESVWE TLSRDLLAVW SKMREVLYPK YIFGGSMIDN
TTTLRGAYEG FRAGGIAGAR EEVRNIAGRV MDTENLLSQG NMSQGLRDWD LWGPLVFCLA
LSLLLSFNAR PEQKSVVFSG VFAMIWIGEA VVTAQIKLLG GNISFAQSVC IIGYTLFPLV
IAALLSALHL PTIPRIPIYI VLIGWSLAAG VSIMGGSGVV KNRVGIAVYP LFVFYVGLGC
LKATMEGSKT PEQAIAHKRS FEEQQDEDSA TMKASEDLKH TRISDREPAE GESSKQEAEV
AKPLSDKGEN ASSITKETTP ERSTRSGAED DGMMEQISSP KKKRVRELDD EAKESDKVNK
ERVPSNGSAT SADRSDRLEP EKKRHRDTLE GGAEAAAIAA ASQQGQRATN GKEEPKTADK
SKGDETEADK QPQKGGDKSA DLPQTSPSAF ASSGFGALAA SSTSGFGALA GKPSVFGGGS
ASPFGGLAAS NTSSGQEETA GDKSTKGAKA GETGSTFGGT FGGGSTTGFG GQASGGFGGG
FGSTFGGGFG GGFAANQPKT LSTFGSANPD TTKAEKPAKA FGAPESDEEE ESGDDGDAEA
DVGSDGGDES STFDDKKKPK LTKVPIHDGE EDEVTLSQFR AKLFAMEPKE GWKERGVGNL
KVNVHKTCVE FDEYTGAPVP GSFDVSLRDD DEDAPPVIAA RLIMRQENTH RVILNTIINR
ALKLEEKPSN AAGKGYMFTA FDGGKPVNML LKLNETNAKL FISEVSGVQS MATIGAAGVP
NKAVLKRKRA ESGDVEGKKD DIAEARVGEE QVATVTPATD NDLPSKPRRG TKAHAALATR
RSASASSSST TSNAVWPASF TTLEKTHRAL NLVFTFCCTR KHLATTFETI KATVEGQLKR
ELKVEDVAKI VALRPTGINF SYVDEASLDV DVREYEKDDP FRGSATKNYQ LSETSQNVEN
TSQGAGKEIL LFEFLDGDLK RGSQQKSEKG AKATRKSKGD ELALPKFSQK QMTALIEKRN
TKFHSAINAF LNRCDSANEN PEEILEKEAQ AYIPKQSNTT VDALESKIDT LPKSIPKERE
SISQIIKEVK DCAWYTGQIV PDGHRVFDPQ EAIYGDLNFI LSQNLVNALY NTKGITQFYS
HQAEAINSLN DGHHVIVATS TSSGKSLIYQ LPVLHELERN SSTRAMYIFP TKALAQDQRR
SLKEMMKFMT GLENTLVETF DGDTAMGDRN IIREEGRIIF TNPDMLHITI LPQEDKWRTF
LQNLKFVVVD EIHVYNGLFG SHVAFIMRRL RRICAALGNR HIKFISCSAT VANPTDHFKT
IFGIEDVRLI DFDGSPSGRK EFLCWNTPFK DPADPSSGRG DAVAESARLF CQLILRGVRV
IAFCKVRHRC EALVAAVKFE LSELGRSDCM ARVMGYRGGY TPQDRRRIES EMFEGKLVGV
IATSALELGV DIGSLDAVIT VGFPYTIANL RQQSGRAGRR NKDSLSVLVG DCFPTDQYYM
QNPDEIFTKP NCELQVDLHN MLVVEGHVQC AAYELPIRPK EDALYFGDSL HSIAEERLEK
DDLGFYHCNE RYRPMPSKFV AIRDTEEDHF AIIDITHGRN IVLEELEASR AFFTLYDGGI
FMHQGNTYLV KEFNPDRKIA RVEHVKVDWT TQQRDFTDID PIETEAMRRI TGSASRAFYG
TIKIQQTVFG FFKIDRRGRK MDAVEVDNPP IIRFSKGMWL DVPKNALDIL IERRLNVAGA
IHAAEHAILS LMPNFVVSMP GDVRTECKVA VKEFAKKETA RKRPARLTFY DAKGGAGGSG
ISTKAFEFVD MLLRQAIQRV EGCHCHDGCV ECVNSEFCKH ANEVMSKAGS QVVLKSLLNM
EIDVDSLPMG PEQFSPSGIE TVVLAEMILP RGRGLMEEKS GAASGMESAA PDRPSGEDSD
VHTIVKVEP
//
