ID A0A093XCY4_TALMA Unreviewed; 875 AA.
AC A0A093XCY4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Helicase POLQ-like {ECO:0000313|EMBL:KFX43063.1};
GN ORFNames=GQ26_0380350 {ECO:0000313|EMBL:KFX43063.1};
OS Talaromyces marneffei PM1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=1077442 {ECO:0000313|EMBL:KFX43063.1, ECO:0000313|Proteomes:UP000029285};
RN [1] {ECO:0000313|EMBL:KFX43063.1, ECO:0000313|Proteomes:UP000029285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PM1 {ECO:0000313|EMBL:KFX43063.1,
RC ECO:0000313|Proteomes:UP000029285};
RX PubMed=25330172; DOI=10.1371/journal.pgen.1004662;
RA Yang E., Wang G., Cai J., Woo P.C., Lau S.K., Yuen K.-Y., Chow W.-N.,
RA Lin X.;
RT "Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms
RT of Dimorphic Transition in Penicillium marneffei.";
RL PLoS Genet. 10:e1004662-e1004662(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX43063.1}.
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DR EMBL; JPOX01000038; KFX43063.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093XCY4; -.
DR HOGENOM; CLU_006553_2_0_1; -.
DR Proteomes; UP000029285; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18026; DEXHc_POLQ-like; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.20; -; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR046931; HTH_61.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048960; POLQ-like_helical.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF20470; HTH_61; 1.
DR Pfam; PF21099; POLQ_helical; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFX43063.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 164..353
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 365..536
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 96022 MW; CFEC40CDC6587385 CRC64;
MSGPPLQSHG FQTSVDTAHQ QTTAIAGLKR PHQNVVSKEP VTAVTTSMTA AATNATTVRQ
SNNSKRRPVD LIRASAATHE TRIAASPIRS VLSGSTANNS GSAIPPLAPP PPAPSQSMLS
SSTSNPLLSL QHPKYGLPPA LVANFQAVGI HSIYPWQASC LLGRGHLTAE KNLLYTAPTG
GGKSLVADVL MLRRVIDNPH RKAILVLPYV ALVQEKLKWL RRIVQGVEKN IDTSASMKQP
WKQPSKEIRV TGFFGGSKSR ATWADTDIAI CTIEKANALV NTAIEECNID DLAVVVVDEI
HMLDDDSRGY LLELMVTKLL LLQQDIQIIG MSATLSSGPV QDAVPPCRKI DPSPFKPLSL
PTANAMVSLA IETATAGFGA EAMPSPSTLD AELLERRLDL VAELGSLPCG LDPVFQNTII
KGVAFHHAGL TTEERELVAE AYDRGTIKVI VATCSLAAGV NLPARRVIMQ GARMGRDIVG
PALLRQMRGR AGRKGKDTVG ETYLICQQAD LEVISEIWDA ETPAIDSCLA QDNKGVKRAL
LEGIATRLVS GREAIDEFMR CTLLCKTREE AEIEKLIETS LQELVNTDLI RLRDDDSYES
TKLGAAIVAS SFSPDDGIFV YEELKRALQA FVMDGEMHIF YMFTPLSVAM NTNIDWLIFR
DQLDQLDESG IRALLFVGVQ PGFVNNMVQT GRNFKEDDPK QLQLSRIYRR AYAAFQLRDL
SNEVPLSTIA SRYNVPRGVV QTLAQTCHGF AAGMVKFCQR MGWGMLAVVL EHMRDRLQAG
ARDDLLEMAQ VTHVKSWTAR LLWENGFRSV RALASTDAKD IIPVLIMARS RKSQSHPNSE
REAERYTEKM TRKAEMIIAS ANKIYERQMQ VEIEE
//
