ID A0A093XH79_9PEZI Unreviewed; 1151 AA.
AC A0A093XH79;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=O988_07432 {ECO:0000313|EMBL:KFX92080.1};
OS Pseudogymnoascus sp. VKM F-3808.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1391699 {ECO:0000313|EMBL:KFX92080.1, ECO:0000313|Proteomes:UP000029329};
RN [1] {ECO:0000313|EMBL:KFX92080.1, ECO:0000313|Proteomes:UP000029329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3808 {ECO:0000313|EMBL:KFX92080.1,
RC ECO:0000313|Proteomes:UP000029329};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX92080.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JPJR01001759; KFX92080.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093XH79; -.
DR STRING; 1391699.A0A093XH79; -.
DR HOGENOM; CLU_000288_125_6_1; -.
DR Proteomes; UP000029329; Unassembled WGS sequence.
DR GO; GO:0005871; C:kinesin complex; IEA:InterPro.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07216; Pat17_PNPLA8_PNPLA9_like3; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002151; Kinesin_light.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46082:SF6; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF01734; Patatin; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 3.
DR PRINTS; PR00381; KINESINLIGHT.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000029329};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 16..227
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REPEAT 823..856
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 949..982
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 1151 AA; 129376 MW; 8950F0C51275EB19 CRC64;
MKPTSREPQD RPLRILSLDG GGIRGISELV ILGEIMHRVE RGLKKESLAS GRILQEATPL
LPADYFDMIC GTSTGGLIAI LLGRLRLSVP EAIDTYRLLA KQVFSERKGR GKDGTFKASN
LEKAMKETIE SKLGKGHADD KMFMTDPVSC KTFVCAVPAM HINNQPRLFR TWSADENPGY
NCMIWEAARA TSAAPTLFKR IYIGDAGIEE EFIDAGLGCN NPVQYLVKEA IKEFGPDRKV
DCIVSIGTGK PKVSGFKAPG LFERVLPLEL IGVLKKMATD SEAEASRMKD RFRNCPGLYH
RLNVERGLET VSLQEWEKLG EVKTHTEAYL NTDAAGEDIG VIVDALVGKP SQAFPLGQLD
GAVATPVNTL SYFLYPSHQV THYVIRKDLV ETIHNHFQSR QDIHQQRLLS YMNHKWFSAI
FWFDASSPTS MAQSFADAAH KLSKPNFDIV DAKGNIQFVR NAIESSNIYW LLVFDNFDDP
KAFDGGDIKE YFPGGGHASV LFTTRDAGVT DMGKSIDLTF MSDQEALELL LKRSQVEKSD
ANTQEGANIV KRLGYHALAI DQAGAYIKAG NLDLCLYMEH YTERKEKVLR EIPDLWDYKR
RLNIDSEVMT RLTVFTTWEL SVQLITGTPT AQKDKIHLLT LAAFLDSKEV SDDLFACYGS
ENIDWLVSCV TDGAWDKYEA QGILKELRKL SLLQNLQIGK HETTFSLHPL IQDWVKLRVK
ADDRQTFALE GILLLSTFLK NDNNKMTLGQ KQALMAHLEV VLQHENKYGI FQGNFEDVEL
QDAAFYFEEF LNSQGQYNLS KQMTEHRLQW RKMFLGNEHP DTLRSMNSFG AALANQGKYR
EAEEIYRQVL KLREKVLGHE HPSTFLSMNN VGTALSDQGK YEEAEQIHRQ VLKLREQVLG
KEHPNTLHNM NSLGVALANQ GKPKEAEKIY RQALKLQQKV LGNEHPDTLL SMNNVGTALG
DQGKYEEAEQ IYRQALKLRE KVLGKEHPST LHSTNSLGAA LGNQGKAEES EQIYRQALQL
QKKILGDEHP DTFLSMSNIG AALSDQGKYA EAEEIHRQTL QLREKVLGKE HPDTLRSMDK
LGVDLFNQGN FDEAIPLQQQ AVQLAEKVLG REHPTTIIIK DNLAKASENS KQKPRLVPIY
TNEPGPEKAM V
//
