ID   A0A093Y4Y1_TALMA        Unreviewed;       351 AA.
AC   A0A093Y4Y1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Zinc-binding alcohol dehydrogenase domain-containing protein cipB {ECO:0000313|EMBL:KFX52503.1};
GN   ORFNames=GQ26_0033540 {ECO:0000313|EMBL:KFX52503.1};
OS   Talaromyces marneffei PM1.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=1077442 {ECO:0000313|EMBL:KFX52503.1, ECO:0000313|Proteomes:UP000029285};
RN   [1] {ECO:0000313|EMBL:KFX52503.1, ECO:0000313|Proteomes:UP000029285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PM1 {ECO:0000313|EMBL:KFX52503.1,
RC   ECO:0000313|Proteomes:UP000029285};
RX   PubMed=25330172; DOI=10.1371/journal.pgen.1004662;
RA   Yang E., Wang G., Cai J., Woo P.C., Lau S.K., Yuen K.-Y., Chow W.-N.,
RA   Lin X.;
RT   "Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms
RT   of Dimorphic Transition in Penicillium marneffei.";
RL   PLoS Genet. 10:e1004662-e1004662(2014).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFX52503.1}.
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DR   EMBL; JPOX01000003; KFX52503.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093Y4Y1; -.
DR   eggNOG; KOG1198; Eukaryota.
DR   HOGENOM; CLU_026673_16_5_1; -.
DR   Proteomes; UP000029285; Unassembled WGS sequence.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   CDD; cd08249; enoyl_reductase_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR   PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR   PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          14..348
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   351 AA;  37246 MW;  96BDB43D8B9056AB CRC64;
     MSTENLAAVL EKVGTALKPL ALPIPSPGEN ELLIRNHAIA ANPADWKLRD FPSHLNNFPT
     VLGSDVCGIV SAIGPNVTKF KVGDRVTGFA LVIANNKPEH GAWQTYTLLQ ESATIRIPEF
     VSYEDGATFP MAFATVAVAY FERLGIARPV LTLDVQQQQQ QQPGMLVWGA SSSTGTAAVQ
     LAKALGIKVF ATSSPKNHEY IKSLGAYAVV DYRDPDVVSK LVQLANEAGT PLQYGFDSIT
     EGNSSLLSAN TLLASGGQGS KLALTGPWPA GDEKPPTGVE TSMTLAAFAF VHHIEMGSWL
     FNEYLPKAIE QKKIVPAPQV RVVDGGIEAA QEALDIVKAG VSATKIVVKV G
//