ID A0A093Y4Z4_9PEZI Unreviewed; 1189 AA.
AC A0A093Y4Z4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Fork-head domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=O988_06506 {ECO:0000313|EMBL:KFX94044.1};
OS Pseudogymnoascus sp. VKM F-3808.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1391699 {ECO:0000313|EMBL:KFX94044.1, ECO:0000313|Proteomes:UP000029329};
RN [1] {ECO:0000313|EMBL:KFX94044.1, ECO:0000313|Proteomes:UP000029329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3808 {ECO:0000313|EMBL:KFX94044.1,
RC ECO:0000313|Proteomes:UP000029329};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX94044.1}.
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DR EMBL; JPJR01001420; KFX94044.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093Y4Z4; -.
DR STRING; 1391699.A0A093Y4Z4; -.
DR HOGENOM; CLU_006221_0_0_1; -.
DR Proteomes; UP000029329; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0060962; P:regulation of ribosomal protein gene transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00059; FH_FOX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR045178; Fhl1/FHA1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR21712:SF29; PRE-RRNA-PROCESSING PROTEIN FHL1; 1.
DR PANTHER; PTHR21712; UNCHARACTERIZED; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000029329}.
FT DOMAIN 358..393
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 662..736
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 662..736
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 215..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 969..1189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..527
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..583
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..642
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..832
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..849
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 867..892
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 969..997
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1059..1160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1189 AA; 128965 MW; CED5429CF45646D6 CRC64;
MTSPHAASDE AVATMVTTAF DDGPTNIELT AADNAAPGAN DIPATTARED ANPEYAEQVT
SIEQLQISAD NDIVEPNLES AAAQPQPIQI KSDLIMEPAI PRTPENNDDD TEYPRVPLGD
YEQLRALSHM LQYQAPPGLA DALNASAMAT LSGNDISMDN ANDPNGPYAE IPQPTRDNDE
TRISAYALLE FEDGQFYMNT YSVILGRDRQ AARNAMRRDA EEAKANMDDH SVAGEPKTPV
RIKREESKYT KSVISESGGI LRDGDDSDSD ERSRRRMHRK ASKKSKSTGS SSNRVSRRQS
LVQPNGKIEY QAQPQARRHA PETAGAVPVD PASLRPSPHD CPLVGIHPPA TTPASGYKAI
SRRHVKIAYN SKKSLFEAEI IGRNGAFVDE VFYYHEDVIP LKSGSYLQIG GVVVRFVLPD
VALGETGAEI PAEHGESGVQ DRYVEGGKEM SFDFDDATRE GALLGDSSDE VSDDADRPEL
GIEGEDDEEG DGDEPGDQQE GSDIDEDNSE LSEVPDEVED GNDDQDEQSK ETLESLPMPQ
KKRGPGRPPK NGIMSKREQQ LAKKEAQQRA AQKTVSQPDT SGKNKVGRPR KNPVDESPVK
TEKRKYTKRK PKDPDALVAK QEGSGDDDRP SKEKKEKKST KPPRSPSPTF NEADLTPEQL
AKPQANYVTL IHEALSNSPT GQMSLPQIYR AIQRRYPFFV LKCNTNGWQS SVRHNLSQHH
AFRKVERDGK GWMWAIVDGV SIEKEKKRRP TPPHQLPPHL HQPIYRAGPH PHMMHGPPGM
MPPPGYAMNH MPPHLRPGQP PQYVGQPMNG YPLPPGQHSM NGAPPPGFPS ALPTAQPMGA
TSNTYSSPYA PKPPANPTQQ APTNTPHNPS QAPPQNVPYQ TPQQPRPIEQ GPPQPDNAMW
RAIDSFRTNL VATMKPKNNK AEALVASSIN RVMGVTSQST ATVVESDLKL EDQIMAALKS
MLKRFPEFNN GTFQQPPQPL GAHTVQQSTQ QPEAAPRQAL AQISPAPTGN AAHAVSDVSS
VKKAPTPGPA VQRPTFIGQA HNRPNGPSVP RPPMMTPGMT RANSGSSANP SFRATTSASP
APPPAANTTL SSGDSTQHQG QHVSGTERND SNQQQLHQSP VNNESSGAAV QPQPTAVVQQ
PPENTQQPGS SNPTTNTNEN GKRPLDEDDV AGGNDFKRLN ASGPPALKT
//
