ID A0A093Y5L0_9PEZI Unreviewed; 1028 AA.
AC A0A093Y5L0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 32.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=O988_03388 {ECO:0000313|EMBL:KFY00301.1};
OS Pseudogymnoascus sp. VKM F-3808.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1391699 {ECO:0000313|EMBL:KFY00301.1, ECO:0000313|Proteomes:UP000029329};
RN [1] {ECO:0000313|EMBL:KFY00301.1, ECO:0000313|Proteomes:UP000029329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3808 {ECO:0000313|EMBL:KFY00301.1,
RC ECO:0000313|Proteomes:UP000029329};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY00301.1}.
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DR EMBL; JPJR01000561; KFY00301.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093Y5L0; -.
DR STRING; 1391699.A0A093Y5L0; -.
DR HOGENOM; CLU_004414_0_1_1; -.
DR Proteomes; UP000029329; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000029329};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 106..267
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 342..1026
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 1028 AA; 114042 MW; 3A3A337282B3F4D2 CRC64;
MDTQVENAIQ IAWDPTSSQA LKGQAFEFLN QLREDASGWQ ICLTLFTRTP QASEVVRVVS
IEIVNNAVAH KHLDEASLAF LKDSLLEYAR RVYGGSSGQE QADSPSLQNK LTQTLTSVFA
YSYQRGWPSF FTDFLSMTCL PNSNSCDNLA GTALYLRILG SVHDEIADVF LSRTGEDQKR
NNDLKDLLRE RDVPKIATSW QEILTYWQGK NDTLVEMCLK VIGRWVNWID ISLVVNQNFL
TILLQLIGRV APSNGEDKVR DAAIGCLTET VGKKMKAGDK MDMIEFLNLG DIVSQLVASP
ALANRFGSDY DVDFAEAVAK LVNGAVFDIV KALEESADGS PTRVKADQQL LIFLPHLLRF
FSDEYDEPCS TVIPSLTDLL TLFRRAQPLP AQYSSMLSPI LNAIITKMRY DDTASWDDQV
TETDGAEFME LRKRLEVLQK IVAAVDQNLY IDVLSNVVGN TFQSIEQTGS GVNWRDIDLA
LHEMYIFGEL AVPNSGLYAK SQPSSVASER LIAMMKKMIE SGIASYNHPA IQLQYMEICV
RYCSFFENQS TFIPQVLEHF VGLVHHNHVR VRTRSWYLFG RFVKHLRAIL GNVAETVISS
ISDLLVIKAE VPKPDDEDDM SSDESDHSAG AVFTSQLYLF EAVGTIASTS TTPVDKKVLY
ARMVLEPLFA NMEQALPAAR NGNAQANLQI HHIIMALGTL AHGFSDWTPG VNSAGSKAPA
DEISQEFNRA AEAILVALES LKSPPEIRTA ARAAFTRLVG TVGARLLPQL SRWISGLLST
ESSKDEMAMF LRVLDQVVFG FKTEIIGVLD SLLSPLLTRI FTSLAEPVSG TDDEIQLGEL
RREYLTFLQV ILNNDLASVL VSETNQGLFD VLLVSVETLA KNVNHGTGHL AASRMAFSIL
AKMAQLWGGP DVATPSHYPE TATPAPTPAF PGFDQFLINR FNPVCWEVLS NRDFRPFQDA
QAKSVLTEIA GLQQTIYSKT GMLFIEHLQQ SFFPSMGFDG SDIIRSMTTS NDRKVFANFL
VAYLKQRA
//
