ID   A0A093YBY4_9PEZI        Unreviewed;       702 AA.
AC   A0A093YBY4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN   ORFNames=O988_02166 {ECO:0000313|EMBL:KFY02429.1};
OS   Pseudogymnoascus sp. VKM F-3808.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1391699 {ECO:0000313|EMBL:KFY02429.1, ECO:0000313|Proteomes:UP000029329};
RN   [1] {ECO:0000313|EMBL:KFY02429.1, ECO:0000313|Proteomes:UP000029329}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3808 {ECO:0000313|EMBL:KFY02429.1,
RC   ECO:0000313|Proteomes:UP000029329};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY02429.1}.
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DR   EMBL; JPJR01000347; KFY02429.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093YBY4; -.
DR   STRING; 1391699.A0A093YBY4; -.
DR   HOGENOM; CLU_021868_0_0_1; -.
DR   Proteomes; UP000029329; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd02961; PDI_a_family; 2.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR46426; PROTEIN DISULFIDE-ISOMERASE TMX3; 1.
DR   PANTHER; PTHR46426:SF1; PROTEIN DISULFIDE-ISOMERASE TMX3; 1.
DR   Pfam; PF00085; Thioredoxin; 2.
DR   Pfam; PF13848; Thioredoxin_6; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 3.
DR   PROSITE; PS51352; THIOREDOXIN_2; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029329};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..702
FT                   /note="Thioredoxin domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001890278"
FT   TRANSMEM        650..670
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          30..181
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   DOMAIN          223..460
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   REGION          211..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        238..253
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   702 AA;  78230 MW;  0698D332BFAC1A70 CRC64;
     MRFLTSTSLL VVGALASLIR AADTKEDVAK GADDSQADDT YTTFNGQKVP QLKEVGDKAL
     DELIQDGYTA VKFYSPSCHH CNAMAPAWKT IYEYYWTSKP VPSTSTGNQE SLNDFHHYYG
     FDFANVNCIA YGDSCIQHGV TGFPVIKIFK DGKAVAEYQR KSDMPAMGVE TIGKFIEETL
     ETIRPGSRVK DGQVWPEAGA SSVEGFSTSA AASTPTAAAK PNTSAAAPAP PKKPKTNKAP
     SSPSNPHGTS VAFTPESFHT QVTLSQDSWF VKFYAPWCHH CQSLAPIWTE LAKEMEGKLN
     IGEVNCEEHK AFCKEAKIEG YPTLAFFSGG ERVDYDGLRG LGDLTRWAGS AIGIGEGVTD
     VTAAEFKTLE ETEEVIFVYF YDHATTSEDF DALDRVILSL IGQATLVKTK DPEMYERFKI
     TTWPRLLVSR DGRPTYYTAL APDDMRDYRL VLQWMQSVWL PIVPELLPGN AREIMDGKLV
     VLAILTRDRQ DEFKAAKNEI KSAAIEWMDK QIHAFQLERQ EYRDAKELRI KEAEAKDDQR
     AVRAAKSIRI DMNRSNRKEV TFAWVDGVFW ERWIRTTYGI NIADGEKVII NDEDNRRYWD
     TTINDNPIIP SRTSILETIP KVITSPPKIK PKYTISSLSK VFFDIRRGAG AHPLLTIGLV
     VAIIVAAVGF GRKRRRSRGG FFRLDDEKNL GLLGGGGNGK VD
//