ID A0A093YEN7_9PEZI Unreviewed; 1169 AA.
AC A0A093YEN7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V490_00160 {ECO:0000313|EMBL:KFY03511.1};
OS Pseudogymnoascus sp. VKM F-3557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFY03511.1, ECO:0000313|Proteomes:UP000029320};
RN [1] {ECO:0000313|EMBL:KFY03511.1, ECO:0000313|Proteomes:UP000029320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFY03511.1,
RC ECO:0000313|Proteomes:UP000029320};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY03511.1}.
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DR EMBL; JPJS01000062; KFY03511.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093YEN7; -.
DR HOGENOM; CLU_002458_2_1_1; -.
DR Proteomes; UP000029320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF53; DOMAIN PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 51..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..668
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 688..715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 736..761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 836..865
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 895..912
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..202
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 225..628
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 640..910
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 1056..1138
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 22..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1169 AA; 128868 MW; 4B77A321A140845D CRC64;
MAAFIVDAVA LHIDLKRGVE SNDPRVGSAR NGTEAGGTLS NATKGTNTSS IAGLLSTLVP
VIVYAAVCML IFWGCRTRYP RVYSPRTILS SLEPHERPKK LPTGWFNWFI PLFKTPDIDV
LHQSSIDGFL FLRFLRILCV ICVFGACVTW PILFPLHILG GGGGKQLDSI SFGNVKKTSW
YFAHAFLAWV FFGFILYMVS RECIYYINLR QAYLLSPYYA KRLSSRTVLF TCVPEQFRDE
ARLRKLFGDS VKNVWIPTYS GDLDDLVKER NQTAYRLEEA EIELIRLANI ERNKVVIRSD
IEANIEAKTP GSEAGSIKGG VPEKAAPPLK ADASPLGLAG GAPPPSDLTE AAATPEVAGN
TSALEPADVA LPASPLEPAD GIVTPPSEVA GEAAPASELT DGAAVPPSDL NAATASPGVT
NETVVSPSMT DGTIASPSNF TDATLASPGL TDATTVSPTS DFAGTTIVSP SSASTGGATM
VKSITKGSKN ETTSTGQTPS QTPNLDSANN EWPGLEWGIQ RGIPDVRGSV AAQWIPVHWR
PTHRPLANYG RRVDTIKWTR DRLKALAPRI YKLRRQHRAG NARRMPAAFV EFDTLSNAQS
AYQTLPHHRP FHMTPHVNGI RPEEIIWSTL RMKWWERIMR KFASTALVAV MVVFWSLPAA
GVGLITKIDV IASKVIFLKW ILLLPKPILG LITGLLPAVA LSLLMAAVPM ILRAIARQSG
VPSYSMIELF VLKRYFIFQV VQVFLVTTLS AAISDSLQSI LEDPLSVRNL LSESLPKASN
FYVSYLILQG LAMSATRVVH LPSLHRAVFA GGRTPRMMST RWHRLKRVHW GTDFPLFANM
GVIVISYSCI APVILAFGAL CFFLVHKVYH YNLLHVYSSE IDTRGLMYPY ALKQILVGVY
LAEICLIGLF GLQAAVGPLL MMFILIITTF LVHISLNDAL GPLLYNLPRS LSVQGLYDDL
AGEPEVPVVE NLETQYDSDF DPGDPNAVTH EELGTRAVEG TKGYSKVAFR FLSSSMREKM
SATSGSVSSF IQDINFWSSW VTPDPADPKP NFFLRWLHPE VFHDFSVLRE KIPTDLPDPE
YTPESLRQAY FQPSLNKIND PTLWIPEDAA GVSKQEVAHS KGIIKITDQS CWMEDRKKGW
HEVRNRGVNV KIRVDFEAES PVVMKRMRY
//
